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ChemicalBook > Product Catalogue >Biochemical Engineering >Natural Products >Silybin

Silybin

Silybin Structure
  • ₹2007 - ₹14722
  • Product name: Silybin
  • CAS: 22888-70-6
  • MF: C25H22O10
  • MW: 482.44
  • EINECS:245-302-5
  • MDL Number:MFCD00872186
  • Synonyms:Silybin-A ,98%;Silybin (50 mg);Silybin, 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin;Silybin，Silymarin;(2R)-2α-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3β,5,7-trihydroxy-4H-1-benzopyran-4-one;(2R,3R)-2-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Flavobion;silliver
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 100MG
  • 1gm
  • 1G
  • 10gm
  • 10G
  • 25gm
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0417
  • Product descriptionSilibinin ≥98% (HPLC)
  • Packaging1G
  • Price₹2662.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS0417
  • Product descriptionSilibinin ≥98% (HPLC)
  • Packaging10G
  • Price₹14343.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2655
  • Product descriptionSilybin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging100MG
  • Price₹14722
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number S 1371
  • Product descriptionSilibinin, ≥98% (HPLC)
  • Packaging1gm
  • Price₹2007
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number S 1371
  • Product descriptionSilibinin, ≥98% (HPLC)
  • Packaging10gm
  • Price₹7002
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number S 1371
  • Product descriptionSilibinin, ≥98% (HPLC)
  • Packaging25gm
  • Price₹9171
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S0417 Silibinin ≥98% (HPLC) 1G ₹2662.95 2022-06-14 Buy
Sigma-Aldrich(India) S0417 Silibinin ≥98% (HPLC) 10G ₹14343.13 2022-06-14 Buy
Sigma-Aldrich(India) PHR2655 Silybin Pharmaceutical Secondary Standard; Certified Reference Material 100MG ₹14722 2022-06-14 Buy
ottokemi S 1371 Silibinin, ≥98% (HPLC) 1gm ₹2007 2022-05-26 Buy
ottokemi S 1371 Silibinin, ≥98% (HPLC) 10gm ₹7002 2022-05-26 Buy
ottokemi S 1371 Silibinin, ≥98% (HPLC) 25gm ₹9171 2022-05-26 Buy

Properties

Melting point :164-174°C
Boiling point :793.0±60.0 °C(Predicted)
alpha :D20 +11° (c = 0.25 in acetone + alcohol)
Density :1.527±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Acetone (Sparingly), DMSO, Methano (Sparingly)
form :Solid
pka :pKa 6.42±0.04 (Uncertain)
color :Pale Yellow
Water Solubility :54mg/L(24.99 ºC)
Merck :13,8607
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
LogP :4.232 (est)
CAS DataBase Reference :22888-70-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Silybin is an inhibitor of a wide variety of proteins, many of which are heavily involved in xenobiotic efflux and metabolism. Silybin is an inhibitor of P-glycoprotein-mediated cellular efflux and also inhibits xenobiotic oxidation by the CYP (cytochrome P450) superfamily of enzymes. This helps to contribute the apoptotic activity of this compound, which has been shown to be effective against a wide variety of cancer cell lines. Silybin is an inhibitor of 5-LO.

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Suppliers and manufacturers

Himpharm A.J Chemicals CLEARSYNTH LABS LTD. Otto Chemie Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd SynZeal Research Pvt Ltd Amantech Chemicals Private Limited Add Biotec Himpharm Pharma Affiliates