Lynestrenol
- CAS No.
- 52-76-6
- Chemical Name:
- Lynestrenol
- Synonyms
- exluten;exluton;lynenol;LYNDIOL;exlution;exlutona;Exlutena;nsc-37725;org485-50;orgametil
- CBNumber:
- CB2441014
- Molecular Formula:
- C20H28O
- Molecular Weight:
- 284.44
- MOL File:
- 52-76-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:03
| Melting point | 158°C |
|---|---|
| alpha | D -13° (chloroform) |
| Boiling point | 366.92°C (rough estimate) |
| Density | 1.0083 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in acetone and in ethanol (96 per cent). |
| form | Solid |
| pka | 13.12±0.40(Predicted) |
| color | Crystals from MeOH |
| Merck | 14,5629 |
| CAS DataBase Reference | 52-76-6 |
| EPA Substance Registry System | Lynestrenol (52-76-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H351-H361 |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| RTECS | RC8964300 |
| HS Code | 2937230000 |
Lynestrenol Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Lynestrenol is an orally available progestogen hormone used in contraception to avoid hereditary angiodema as well as in treatment of ischemic stroke.
World Health Organization (WHO)
Lynestrenol, a synthetic progestogen, was introduced in the early 1960s as a component in oral contraceptive preparations. In 1967, as a result of new regulations required by the United States Food and Drug Administration, lynestrenol was submitted to long-term toxicity studies and by the early 1970s it was shown to be associated with an increased incidence of mammary tumours in beagle bitches which led to its withdrawal by at least one regulatory authority. Subsequently the validity of the beagle bitch model as a predictor of carcinogenicity of steroid contraceptives has been contested by many national regulatory authorities and lynestrenol remains available in some countries for contraceptive and other purposes. (Reference: (WHODI) WHO Drug Information, 1-3, 5-7, 1984)
Safety Profile
An experimental teratogen.Experimental reproductive effects. Human reproductiveeffects by ingestion and implant routes: menstrual cyclechanges or disorders, female fertility index, other fertilitychanges and effects on females. Questionable carcinoge
Lynestrenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Asg Biochem Pvt. Ltd | +91-9650436669 +91-9650436669 | New Delhi, India | 25 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Vincit Labs Pvt Ltd | +91-1127357490 +91-1127357490 | New Delhi, India | 15 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Famy Care Ltd. | 08048372743Ext 214 | Ahmedabad, India | 1 | 58 | Inquiry |
| Swati Spentose Pvt. Ltd. | +91 22 66332427 | New Delhi, India | 17 | 58 | Inquiry |
| ASG Biochem Pvt. Ltd | 09432255551 | Delhi, India | 3 | 58 | Inquiry |