TRIMETHYLSILYL ISOTHIOCYANATE
- CAS No.
- 2290-65-5
- Chemical Name:
- TRIMETHYLSILYL ISOTHIOCYANATE
- Synonyms
- ISOTHIOCYANATOTRIMETHYLSILANE;TRIMETHYLSILYL ISOTHIOCYANATE;isothiocyanatotrimethyl-silan;Trimethylsilylisothiocyanate,94%;Silane, isothiocyanatotrimethyl-;Trimethylsilyl isothiocyanate,97%;(TriMethylsilyl)isothiocyanate 99%
- CBNumber:
- CB2460765
- Molecular Formula:
- C4H9NSSi
- Molecular Weight:
- 131.27
- MOL File:
- 2290-65-5.mol
- Modify Date:
- 2023/5/9 9:30:36
| Melting point | −32.8 °C(lit.) |
|---|---|
| Boiling point | 143 °C(lit.) |
| Density | 0.931 g/mL at 25 °C(lit.) |
| vapor density | >1 (vs air) |
| refractive index |
n |
| Flash point | 95 °F |
| storage temp. | 2-8°C |
| form | liquid |
| Specific Gravity | 0.931 |
| Water Solubility | Reacts with water. |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 1745262 |
| InChIKey | XLTUPERVRFLGLJ-UHFFFAOYSA-N |
| CAS DataBase Reference | 2290-65-5(CAS DataBase Reference) |
| EPA Substance Registry System | Isothiocyanatotrimethylsilane (2290-65-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H301+H311+H331-H315-H319-H334-H335 | |||||||||
| Precautionary statements | P210-P280-P301+P310-P303+P361+P353-P304+P340+P311-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 10-23/24/25-36/37/38-42 | |||||||||
| Safety Statements | 23-26-36/37-45 | |||||||||
| RIDADR | UN 1992 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-19-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
TRIMETHYLSILYL ISOTHIOCYANATE price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 230766 | (Trimethylsilyl)isothiocyanate 99% | 2290-65-5 | 10G | ₹3030 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 230766 | (Trimethylsilyl)isothiocyanate 99% | 2290-65-5 | 50G | ₹12090 | 2022-06-14 | Buy |
| ALFA India | ALF-L03277-14 | Trimethylsilyl isothiocyanate, 94% | 2290-65-5 | 25g | ₹7553 | 2022-05-26 | Buy |
| ALFA India | ALF-L03277-06 | Trimethylsilyl isothiocyanate, 94% | 2290-65-5 | 5g | ₹2379 | 2022-05-26 | Buy |
TRIMETHYLSILYL ISOTHIOCYANATE Chemical Properties,Uses,Production
Chemical Properties
clear colorless to light yellow liquid
Uses
Trimethylsilyl isothiocyanate is used as derivatizing reagent during the synthesis of amino acid thiohydantoins. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.
General Description
Trimethylsilyl isothiocyanate (TMS-ITC) reacts with fullerene-mixed peroxide C60(O)(OOtBu)4 to yield isothiocyanate derivative C60(NCS)(OH)(OOtBu)4. TMS-ITC undergoes condensation with ethyl 2-benzylamino-5-methyl-3-phenylcyclopent-1-enecarboxylate to yield 1-benzyl-5-methyl-7-phenyl-2-thioxo-1,2,3,5,6,7-hexahydrocyclopentapyrimidin-4-one. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.
Purification Methods
The 1H NMR spectrum should have only one peak; if not purify it by repeated fractionation in an all-glass system using a 50cm (4mm internal diameter) column without packing. [Anderson J Am Chem Soc 69 3049 1947, Fehér & Blümcke Chem Ber 90 1934 1957, Neidleim & Hege Synthesis 51 1975, Beilstein 4 III 1861, 4 IV 4011.]
TRIMETHYLSILYL ISOTHIOCYANATE Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
1of2
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16220 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | China | 9003 | 58 | Inquiry |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | China | 35451 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Qingdao Dexin Chemical Co., Ltd | +86-15553333686 +86-15553333686 | China | 2865 | 58 | Inquiry |
| ABCR GmbH & CO. KG | 49 721 95061 0 | Germany | 6846 | 75 | Inquiry |
2290-65-5(TRIMETHYLSILYL ISOTHIOCYANATE)Related Search:
1of4
chevron_right