Dihydrotachysterol
- CAS No.
- 67-96-9
- Chemical Name:
- Dihydrotachysterol
- Synonyms
- dht2;AT-10;C06957;Dygrayl;Tachyrol;dihydral;dygratyl;parterol;HSDB3314;dht(sub2)
- CBNumber:
- CB2469405
- Molecular Formula:
- C28H46O
- Molecular Weight:
- 398.66
- MOL File:
- 67-96-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:03
Melting point | 116-120°C |
---|---|
alpha | D22 +97.5° (chloroform) |
Boiling point | 461.8°C (rough estimate) |
Density | 0.9678 (rough estimate) |
refractive index | 1.5100 (estimate) |
storage temp. | 2-8°C |
solubility | Practically insoluble in water, freely soluble in acetone and hexane, sparingly soluble in ethanol (96 per cent). |
pka | 14.96±0.40(Predicted) |
form | Solid |
color | White to off-white |
Stability | Light sensitive |
InChIKey | ILYCWAKSDCYMBB-KWOSLRGBSA-N |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H301-H413 |
Precautionary statements | P264-P270-P273-P301+P310-P405-P501 |
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 36 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | WW0600000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 2936299055 |
Toxicity | LD50 oral in mouse: 288mg/kg |
Dihydrotachysterol Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Calcium regulator. Preparation by reduction of Tachysterol. It is widely used for hypocalcemic hypoparathyroidism following surgical removal of parathyroids.
Definition
ChEBI: A hydroxy seco-steroid that is 9,10-secoergosta-5,7,22-triene substituted by a hydroxy group at position 3. A synthetic analogue of vitamin D that acts a bone density conservation agent.
Purification Methods
Crystallise the sterol from 90% MeOH, UV: max at 242, 251 and 261nm (E1% 760, 1010 and 650) in EtOH. The acetate has m108-110o and [] +32.8o (CHCl3), UV: max at 242, 251 and 261nm (E 780, 910 and 600) in EtOH. The propionate has m 97-98o and [] +37o (CHCl3), UV: max 242, 251 and 261nm (E 750, 860 and 570) in EtOH. [Werder Hoppe Seyler's Z Physiol Chem 260 119 1939, Windaus et al. Justus Liebigs Ann Chem 499 1978 1932, Beilstein 6 III 2833, 6 IV 3994, 4161.]
Dihydrotachysterol Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Dishman Carbogen Amcis Ltd (Dishman Group) | +91-2717420100 +91-8154017093 | Gujarat, India | 90 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Swapnroop Drugs & Pharmaceuticals | 08048371984Ext 910 | Maharashtra, India | 20 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24099 | 58 | Inquiry |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
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