4-CHLOROMERCURIBENZOIC ACID

- CAS No.
- 59-85-8
- Chemical Name:
- 4-CHLOROMERCURIBENZOIC ACID
- Synonyms
- DYR;P-CMB;P-CMBA;usafd-3;NSC 32866;DHFR from mouse;p-Chlormercuribenzoic Acid;P-CHLOROMERCURIBENZOIC ACID;4-CHLOROMERCURIBENZOIC ACID;p-(chloromercuri)-benzoicaci
- CBNumber:
- CB2470894
- Molecular Formula:
- C7H5ClHgO2
- Molecular Weight:
- 357.16
- MOL File:
- 59-85-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
Melting point | 287 °C (dec.)(lit.) |
---|---|
storage temp. | -20°C Freezer |
solubility | Aqueous Base (Slightly, Heated), |
form | solid |
biological source | mouse |
BRN | 3662892 |
CAS DataBase Reference | 59-85-8(CAS DataBase Reference) |
EPA Substance Registry System | Mercurate(1-), (4-carboxylatophenyl)chloro-, hydrogen (59-85-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H319 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313 |
Hazard Codes | T+,N |
Risk Statements | 26/27/28-33-50/53 |
Safety Statements | 13-28-36-45-60-61 |
RIDADR | UN 2025 6.1/PG 2 |
WGK Germany | 3 |
RTECS | OV8050000 |
F | 3-8-10 |
TSCA | Yes |
HazardClass | 6.1(a) |
PackingGroup | II |
4-CHLOROMERCURIBENZOIC ACID price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SRP6119 | DHFR from mouse recombinant, expressed in E. coli, ≥95% (SDS-PAGE) | 59-85-8 | 100μG | ₹45554.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C5913 | 4-Chloromercuribenzoic acid cysteine active site modifier | 59-85-8 | 5G | ₹21639.18 | 2022-06-14 | Buy |
4-CHLOROMERCURIBENZOIC ACID Chemical Properties,Uses,Production
Chemical Properties
4-CHLOROMERCURIBENZOIC ACID is White Solid
Uses
4-CHLOROMERCURIBENZOIC ACID can be used to inhibit some enzymes that require unmodified cysteine residues (e.g., adenylyl cyclase).
Safety Profile
Poison by intraperitoneal route. See also MERCURY COMPOUNDS. When heated to decomposition it emits very toxic fumes of Cland Hg.
Purification Methods
Its suspension in water is stirred with enough 1M NaOH to dissolve most of it: a small amount of insoluble matter is removed by centrifugation. The chloromercuribenzoic acid is then precipitated by adding 1M HCl and centrifuged off. The precipitation is repeated twice. Finally, the precipitate is washed three times with distilled water (by centrifugation), then dried in a thin layer under vacuum over P2O5 [Boyer J Am Chem Soc 76 4331 1954]. Chloromethylphosphonic acid dichloride [1983 -26 -2] M 167.4, b 50o/0.5mm, 52 -53(59)o/2mm, 63-65o/3mm, 78 -79o/10mm, 87 -88o/15mm, 102-103o/30mm, d 4 1.638, n D 1.4971. It is fractionally distilled using a short Claisen column and redistilled. The aniline salt has m 199-201o. The 3 1P NMR has a single peak at -38±2 ppm from 85% H3PO4. [Kinnear & Perren J Chem Soc 3437 1952, NMR: van Wazer et al. J Am Chem Soc 78 5715 1956, McConnell et al. J Org Chem 22 462 1957, Beilstein 1 III 2593, 1 IV 3068.]
4-CHLOROMERCURIBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 7859 | 58 | Inquiry |
LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43340 | 58 | Inquiry |
ABCR GmbH & CO. KG | 49 721 95061 0 | Germany | 6831 | 75 | Inquiry |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-81148696 18161915376 | China | 9799 | 58 | Inquiry |
Eastern Chemical Corp. | 631 273-0900 | United States | 2786 | 34 | Inquiry |
Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6650 | 58 | Inquiry |
Sigma-Aldrich | 021-61415566 800-8193336 | China | 51456 | 80 | Inquiry |
TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Japan | 28387 | 80 | Inquiry |
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