Oxybutynin
- CAS No.
- 5633-20-5
- Chemical Name:
- Oxybutynin
- Synonyms
- Oxytrol;OXYBUTININ;OXYBUTYNIN;Oxibutynin;Oxibutyninum;(RS)-Oxybutynin;OXYBUTYNIN BASE;(+/-)-OXYBUTYNIN;Oxybutynin(Ditropan);Oxybutynin USP/EP/BP
- CBNumber:
- CB2767266
- Molecular Formula:
- C22H31NO3
- Molecular Weight:
- 357.49
- MOL File:
- 5633-20-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:04
| Boiling point | 494.4±45.0 °C(Predicted) |
|---|---|
| Density | 1.097±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | ≥ 17.9mg/mL in DMSO |
| pka | 8.04(at 25℃) |
| form | Powder |
| color | White to off-white |
| CAS DataBase Reference | 5633-20-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H312-H332-H302 |
| Precautionary statements | P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501 |
Oxybutynin Chemical Properties,Uses,Production
Uses
Oxybutynin(Ditropan) is an anticholinergic medication used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder.Oxybutynin contains one
Uses
Oxybutynin is intended for relieving unpleasant symptoms associated with emptying the intestine or urinary bladder. A
General Description
Oxybutynin, 4-Diethylaminobut- 2-ynyl2-cyclohexyl-2- hydroxy-2-phenyl-ethanoate, (Oxytrol) wasone of the first agents specifically developed to exploit the effectsthat cholinergic blocking agents have on the bladder. Bycompetitively blocking the muscarinic receptors, it has directspasmolytic effects on bladder smooth muscle. This reductionin smooth muscle tone allows for greater volumes of urine tobe stored in the bladder, which results in less urinary incontinence,urgency, and frequency. Oxybutynin acts as a competitiveantagonist on M1, M2, and M3 receptor subtypes.
Synthesis
Oxybutynin, 4-diethylamino-2-butynylic ester |á-phenylclohexaneglycolic acid (14.1.35), is synthesized either by a Mannich reaction using propargyl ester of |á-phenyl-|á-cyclohexaneglycolic acid, paraform and diethylamine, or transesterification of the methyl ester of |á-phenyl-|á-cyclohexaneglycolic acid using 1-acetoxy-4-diethylamino- 2-butene in the presence of sodium methoxide [26].
Oxybutynin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Chempifine Chemicals | +91-2225667766 +91-2225667766 | Punjab, India | 144 | 58 | Inquiry |
| Harman Finochem Ltd | +91-2226528080 +91-2226528080 | Maharashtra, India | 37 | 58 | Inquiry |
| Besil Chem LLP | +91-7760252666 +91-9880731835 | Bangalore, India | 163 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Triveni Interchem Private Limited (Group Of Triveni... | 08046042087 | Gujarat, India | 497 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Chempifine Chemicals | 58 |
| Harman Finochem Ltd | 58 |
| Besil Chem LLP | 58 |
| Ralington Pharma | 58 |
| Varanous Labs Pvt Ltd | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| SynZeal Research Pvt Ltd | 58 |
| Triveni chemicals | 58 |
| Triveni Interchem Private Limited (Group Of Triveni... | 58 |
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