5-(Ethylthio)-1H-tetrazole
- CAS No.
- 89797-68-2
- Chemical Name:
- 5-(Ethylthio)-1H-tetrazole
- Synonyms
- ETT;ACTIVATOR;ETT Activator;ACTIVATOR REAGENT;5-Ethyltio-1H-Tetrazole;UT2H;OCTN1;SLC22A4;Ethylthio H;5-(Ethylthio)-1
- CBNumber:
- CB3104462
- Molecular Formula:
- C3H6N4S
- Molecular Weight:
- 130.17
- MOL File:
- 89797-68-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
Melting point | 72-80 °C(lit.) |
---|---|
Boiling point | 81-82 °C |
Density | 0.786 g/mL at 25 °C |
Flash point | 42 °F |
storage temp. | 2-8°C |
solubility | soluble, clear, colorless |
form | buffered aqueous solution |
pka | 3.89±0.10(Predicted) |
color | solid white |
InChIKey | GONFBOIJNUKKST-UHFFFAOYSA-N |
CAS DataBase Reference | 89797-68-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS05,GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H225-H302+H312+H332-H315-H318 | |||||||||
Precautionary statements | P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338 | |||||||||
Hazard Codes | Xi,Xn,F | |||||||||
Risk Statements | 36/37/38-44-36-20/21/22-11-5 | |||||||||
Safety Statements | 26-35-36/37-16-36 | |||||||||
RIDADR | UN 1648 3/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Irritant | |||||||||
HazardClass | 4.1 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29299000 | |||||||||
NFPA 704 |
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5-(Ethylthio)-1H-tetrazole price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | L030000 | ETT Activator 0.25 M | 89797-68-2 | 6X450ML | ₹40507.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SAB1304892 | ANTI-SLC22A4 (C-TERM) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 89797-68-2 | 400μL | ₹47796.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L030000 | ETT Activator 0.25 M | 89797-68-2 | 4X2L | ₹97338.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L030000 | ETT Activator 0.25 M | 89797-68-2 | 4X2.5L | ₹113478.48 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L0302511 | ETT Activator | 89797-68-2 | 4X2.5L | ₹121640.53 | 2022-06-14 | Buy |
5-(Ethylthio)-1H-tetrazole Chemical Properties,Uses,Production
Chemical Properties
White crystals
Application
5-(Ethylthio)-1H-tetrazole is used a powerful activator in DNA and RNA syntheses.
Preparation
5-(Ethylthio)-1H-Tetrazole is prepared from the corresponding alkyl thiocyanate and sodium azide through a [2?+?3] cycloaddition under phase transfer catalytic conditions (eq 1). The ratio of the solvent (water to toluene) as well as the reaction temperature are important factors in obtaining preparative yields of the alkylthiotetrazoles. 5-Ethylthio-1H-tetrazole has also been prepared using DMF as solvent albeit in much lower yield.
General Description
5-(Ethylthio)-1H-tetrazole (ETT) is an efficient activator, that activates nucleoside phosphoramidites towards condensation with a nucleoside to form dinucleoside phosphates during oligonucleotide synthesis.
Purification Methods
recrystallized from toluene.
5-(Ethylthio)-1H-tetrazole Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
GRK RESEARCH LABORATORIES PVT LTD | +91-8249607014 +91-9849401944 | Hyderabad, India | 205 | 58 | Inquiry |
3A Chemie Private Limited | +91-91-712-2564285 +91-9766589212 | Maharashtra, India | 57 | 58 | Inquiry |
Corvine Chemicals and Pharmaceuticals Ltd. | +91-23354873 +91-4023354928 | Telangana, India | 12 | 58 | Inquiry |
ChemGenes India Pvt Ltd | +91-8687421036 +91-8687421036 | Uttar Pradesh, India | 16 | 58 | Inquiry |
Dr Chindepalli | 91-7036227677 | Hyderabad, India | 486 | 58 | Inquiry |
Vivera Labs | 91-9912882943 | Hyderabad, India | 24 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |