ChemicalBook > Product Catalog >API >Circulatory system drugs >Antihypertensive drugs >Lisinopril Dihydrate
Lisinopril Dihydrate
- CAS No.
- 83915-83-7
- Chemical Name:
- Lisinopril Dihydrate
- Synonyms
- Lisinopril;Zestfil;renacor;isinopriL;Lisinopril API;(S) Lisinopril;L-154826：MK-521;LISINOPRIL HYDRATE;Lisinopril99%Assay;MK-521 (dihydrate)
- CBNumber:
- CB3113756
- Molecular Formula:
- C21H33N3O6
- Molecular Weight:
- 423.51
- MOL File:
- 83915-83-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/16 10:38:43
| Melting point | 148 °C |
|---|---|
| alpha | 25405 -120° (c = 1 in 0.25M pH 6.4 zinc acetate); 25436 -96° (c = 1 in 0.25M pH 6.4 zinc acetate) |
| refractive index | -45 ° (C=1, 0.25mol/L Zinc Acetate Buffer) |
| storage temp. | 2-8°C |
| solubility | H2O: ≥10 mg/mL |
| pka | 2.5, 4.0, 6.7, 10.1(at 25℃) |
| form | solid |
| color | white |
| Merck | 14,5516 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 83915-83-7(CAS DataBase Reference) |
| EPA Substance Registry System | L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, hydrate (1:2) (83915-83-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360D-H373 |
| Precautionary statements | P202-P260-P280-P308+P313-P405-P501 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 22-24/25-36 |
| WGK Germany | 3 |
| RTECS | TW3589990 |
| HazardClass | IRRITANT |
| HS Code | 2933995300 |
Lisinopril Dihydrate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR1143 | Lisinopril Pharmaceutical Secondary Standard; Certified Reference Material | 83915-83-7 | 1G | ₹11355.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L6292 | Lisinopril ≥98% (HPLC) | 83915-83-7 | 100MG | ₹43668.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L6292 | Lisinopril ≥98% (HPLC) | 83915-83-7 | 250MG | ₹88321.18 | 2022-06-14 | Buy |
| TCI Chemicals (India) | L0220 | Lisinopril Dihydrate | 83915-83-7 | 1G | ₹5200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | L0220 | Lisinopril Dihydrate | 83915-83-7 | 5G | ₹11100 | 2022-05-26 | Buy |
Lisinopril Dihydrate Chemical Properties,Uses,Production
Description
Lisinopril is an angiotensin converting enzyme inhibitor structurally related to enalaprilat. It is reportedly useful in the management of hypertension and congestive heart failure.
Chemical Properties
White to Off-White Crystalline Powder
General Description
Lisinopril, 1-[N2-[S-1-carboxy-3-phenylpropyl]-L-lysyl]-L-proline dihydrate (Prinivil, Zestril), is alysine derivative of enalaprilat, the active metabolite ofenalapril. Like all ACE inhibitors, it is an active site-directedinhibitor of the enzyme, with the zinc ion used in an effectivebinding interaction at a stoichiometric ratio of 1:1. The pharmacologicaleffects of lisinopril are similar to those of captopriland enalapril.
Clinical Use
Many new ACE inhibitors became available for the treatmentof hypertension following the clinical effectivenessof enalapril. Enalapril is a non–thiol-containing ACE inhibitordevoid of the side effects of rash and loss of thesense of taste characteristic of the thiol-containing compoundcaptopril. With the exception of the phosphoruscontainingfosinopril, these antihypertensive agents havea 2-, like the prototypical drug captopril,are used in the treatment of mild-to-moderate hypertension,either alone or in conjunction with diuretics orcalcium channel blockers.
Lisinopril Dihydrate Preparation Products And Raw materials
Raw materials
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Global( 375)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| chakrachem Lifesciences | +91 9902744663 | Hyderabad, India | 451 | 58 | Inquiry |
| KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| Unimark Remedies Ltd | +91-2267304120 +91-2267304120 | Maharashtra, India | 48 | 58 | Inquiry |
| Melody Healthcare Private Limited | 09011948112 | Mumbai, India | 7 | 58 | Inquiry |
| IPCA Laboratories Limited | +91 (22) 6210 5000 | New Delhi, India | 56 | 58 | Inquiry |
| Samchem India | 91-011-45020538 | Delhi, India | 48 | 58 | Inquiry |
| Opulent Pharma | 08068441147Ext 981 | Gujarat, India | 810 | 58 | Inquiry |
| Innovative Synthetic Molecules | +91 40-24111684 | Hyderabad, India | 527 | 58 | Inquiry |
| Ayon PharmaChem | 91-22-28638348 | Maharashtra, India | 303 | 58 | Inquiry |
| Mehta Medicare Private Limited | +91 33 2476 7882 | Kolkata, India | 8 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| chakrachem Lifesciences | 58 |
| KARPSCHEM LABORATORIES | 58 |
| Unimark Remedies Ltd | 58 |
| Melody Healthcare Private Limited | 58 |
| IPCA Laboratories Limited | 58 |
| Samchem India | 58 |
| Opulent Pharma | 58 |
| Innovative Synthetic Molecules | 58 |
| Ayon PharmaChem | 58 |
| Mehta Medicare Private Limited | 58 |
83915-83-7(Lisinopril Dihydrate)Related Search:
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Lisinopril Related Compound A (15 mg) ((S)-2-{(3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl}-4-phenylbutanoic acid)
(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate
LIQUID PRED (prednisone),Lisinopril
Lisinopril API
Lisinopril (Zestril)
Lisinopril for system suitability A
Lisinopril for peak identification
N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline,hydrate (1:2)
Lisinopril for system suitability
LISINOPRIL-D5 HYDRATE
LISINOPRIL HYDRATE
(ds)-1-[n2-(1-carboxy-3-phenylpropyl)-l-prolinedihydrate
(s)-1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-l-prolinedihydrate
(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521
L-154826：MK-521
Zestfil
(S) -1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-praline dihydrate
(2S)-1-[(2S)-6-Amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid dihydrate
(S)-(-)-1-[N-(1-Carboxy-3-phenylpropyl)-L-lysinyl]-L-proline dihydrate
Lisinopril,(S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, MK-521
Lisinopril (300 mg)
1-(n(sup2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-,dihydrate,(s)-l-prolin
renacor
N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]5-methylpyrazinecarboxamide dihydrate
Lisinopril dihydrate USP24,25 EP2000(III)
(S) Lisinopril
(S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]L-proline, Dihydrate, MK-521, Acerbon, Alapril, Carace, Coric, Novatec, Prinil, Prinivil, Tensopril, Vivatec, Zestril
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-propyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
Lisinopril99%Assay
LisinoprilC21H31H305*2H20
1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline
(S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate
LISINOPRIL DEHYDRATE
(S)-1-{(S)-6-Amino-2-[((S)-1-carboxy-3-phenyl)propylamino]hexanoyl}pyrrolidine-2-carboxylic acid dihydrate
LISINOPRIL DIHYDRATE
(2S)-1-[(2S)-6-Amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino] hexanoyl] pyrrole-2-carboxylic acid dihydrate
Lisinopril 83915-83-7
LISINOPRI (DIHYDRATE) (LMK-521 (DIHYDRATE))
(S)-Lisinopril Dihydrate
LisinoprilDihydrate>
Lisinopril for peak identification CRS
Lisinopril dihydrate CRS
Lisinopril for system suitability A CRS
MK-521 (dihydrate)
isinopriL
Lisinopril Dihydrate USP/EP/BP
Lisinopril hydrate (MK-521)
Lisinopril DihydrateQ: What is
Lisinopril Dihydrate Q: What is the CAS Number of
Lisinopril Dihydrate Q: What is the storage condition of
Lisinopril Dihydrate
"Lisinopril for system suitability (Y0001235)"Q: What is
"Lisinopril for system suitability (Y0001235)" Q: What is the CAS Number of
"Lisinopril for system suitability (Y0001235)"
Lisinopril (1368609)
Lisinopril
Lisinopril diydrate
Lisinopril Dihydrate
(S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-proline Dihydrate
Lisinopril Dihydrate, ≥ 98.0%
Renopril dihydrate
83915-83-7
C21H31O5N32H2O
C13H31N3O52H2O