ChemicalBook > Product Catalog >Organic Chemistry >Nitrogen Compounds >O-Desmorpholinopropyl Gefitinib
O-Desmorpholinopropyl Gefitinib
- CAS No.
- 184475-71-6
- Chemical Name:
- O-Desmorpholinopropyl Gefitinib
- Synonyms
- 4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol;FAAH-IN-2;Des-Gefitinib;N-(3-Chloro-4-f;FAAH inhibitor 2;Gefitinib iMpurity C;Gefitinib Intermediate 1;Gefitinib interMediate VII;FAAH-IN-2 (Gefitinib Impurity);O-Desmorpholinopropyl Gefitinib
- CBNumber:
- CB31176644
- Molecular Formula:
- C15H11ClFN3O2
- Molecular Weight:
- 319.72
- MOL File:
- 184475-71-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/27 11:08:09
| Melting point | >260°C (dec.) |
|---|---|
| Boiling point | 478.8±45.0 °C(Predicted) |
| Density | 1.489±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Very Slightly, Heated) |
| form | Solid |
| pka | 8.18±0.40(Predicted) |
| color | Pale Beige to Beige |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933.59.8000 |
O-Desmorpholinopropyl Gefitinib price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | C3647 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol | 184475-71-6 | 1G | ₹2600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C3647 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol | 184475-71-6 | 5G | ₹8700 | 2022-05-26 | Buy |
O-Desmorpholinopropyl Gefitinib Chemical Properties,Uses,Production
Description
O-Desmorpholinopropyl Gefitinib is a metabolite of Gefitinib, a potent inhibitor of tyrosine phosporylation in EGFR. The chemical structure of O-Desmorpholinopropyl Gefitinib consists of a quinazoline-6-ol core with a phenylamino group attached to a chloro-fluoro-phenyl ring, enabling it to interact with multiple biological targets. It is involved in inhibiting enzymes such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).
Chemical Properties
Tan Solid
O-Desmorpholinopropyl Gefitinib Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 214)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Raising Sun Pharma | +91-9399941155 +91-9399941155 | Telangana, India | 127 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Trignokem International | +91 (40) 2717-0709 | New Delhi, India | 380 | 50 | Inquiry |
| Manus Aktteva | +91 (79) 6512-3395 | New Delhi, India | 581 | 34 | Inquiry |
| KKyemistry (India) Pvt. Ltd. | +91 (40) 2351-0950 | New Delhi, India | 197 | 50 | Inquiry |
184475-71-6(O-Desmorpholinopropyl Gefitinib)Related Search:
Gefitinib Impurity 11
Gefitinib-d6
6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
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1of4
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FAAH-IN-2
4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline
4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol
O-Desmorpholinopropyl Gefitinib
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Gefitinib interMediate VII
4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
Gefitinib Intermediate 1
4-(3-Chloro-4-fluoroanilino)-6-hydroxy-7-methoxyquinazoline
N-(3-Chloro-4-f
6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)aMino]-7-Methoxy-
Gefitinib iMpurity C
FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib)
Gefitinib Impurity 12 (O-Desmorpholinopropyl Gefitinib)
FAAH inhibitor 2
Gefitinib O-Desmorpholinopropyl Impurity
4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-ol
Des-Gefitinib
FAAH-IN-2 (Gefitinib Impurity)
4- (3-Chloro-4-fluorophenylamino) -7-methoxyquinoline-6-alcohol
184475-71-6
C15H11ClFN3O2
Gefitinib
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals