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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Structure
CAS No.
199327-61-2
Chemical Name:
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
Synonyms
Gefitinib-8;quinazolin-4(3H);Gefitinib iMpurity F;Gefitinib Impurity 14;Gefitinib Impurity 17;Gefintinib Impurity 5;Getitinib interMediate;Gefitinib impurities135;Gefitinib impurities132;InterMediate of Gefitinib
CBNumber:
CB21477111
Molecular Formula:
C16H21N3O4
Molecular Weight:
319.36
MOL File:
199327-61-2.mol
MSDS File:
SDS
Modify Date:
2024/7/12 17:58:41
Request For Quotation

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Properties

Melting point 233-236 °C
Boiling point 519.5±60.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 7.10±0.10(Predicted)
color White to Off-White
CAS DataBase Reference 199327-61-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P260-P273-P280-P312
HS Code  2933599590

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Chemical Properties,Uses,Production

Description

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells.

Chemical Properties

White Solid

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

6-Acetoxy-4-chloro-7-methoxyquinazoline Gefitinib

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Suppliers

Global( 278)Suppliers
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SCIKEM PHARMACEUTICALS PVT LTD +91-9959455992 +91-9959455992 Telangana, India 14 58 Inquiry
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Supplier Advantage
SCIKEM PHARMACEUTICALS PVT LTD 58
R SCIENTIFIC 58
RANI LIFE SCIENCES PVT LTD 58
VGS SYNTHESIS PRIVATE LIMITED 58
ACE BIOSCIENCES 58
VINEET LABORATORIES LIMITED 58
Ability Life Sciences 58
Basil Drugs AND Pharmaceuticals Pvt Ltd 58
Rivashaa Agrotech Biopharma Pvt. Ltd. 58
Pratap Organics Pvt Ltd 58

199327-61-2(7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one)Related Search:

Methoxydiethylborane m-Anisyl alcohol p-Anisidine POLY(ETHYLENE GLYCOL) METHYL ETHER ACRYLATE 4-Methoxybenzoic acid
p-Anisaldehyde Anisole Methoxyacetic acid (Trifluoromethoxy)benzene Gefitinib-d6
Gefitinib 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate
4-(3-Chloropropyl)morpholine Gefitinib Impurity 11 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one
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7-Methoxy-6-(3-Morpholin-4-ylpropoxy) Quinazolin- 4-(3H)-One Gefitinib HCL InterMediates G5 Getitinib interMediate Gefitinib iMpurity F 7-METHOXY-6-(3-MORPHOLINOPROPOXY)QUINAZOLIN-4(3H)-ONE 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 7-Methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one 7-Methoxy-6-[3-(4-morpholinyl)propoxy]-4(3H)-quinazolinone Gefitinib Impurity 14 7-methoxy-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-4-one 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quainazolin-4(3H)-one 6-(3-morpholinopropoxy)-7-methoxyquinazolin-4(3H)-one 7-Methoxy-6-(3-morpholinopropoxy) quinazolin-4(3H) 7-Methoxy-6-(3-morpholin-4-yl-propoxy)-3H-quinazolin-4-one 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin 7-Methoxy-6-[3-(Morpholin-4-yl)propoxy]-3,4-dihydroquinazolin-4-one InterMediate of Gefitinib 7-Methoxy-6-(3-Morpholin-4-yl-propoxy) -4-(3H)-quinazolinone Gefitinib Impurity 17 Gefintinib Impurity 5 Gefitinib-8 4(3H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]- 7-METHOXY-6-(MORPHOLIN-4-YL PROPY L)QUINAZOLIN-4-(3H)-ONE Gefitinib impurities135 Gefitinib impurities132 TIANFU-CHEM - 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one 7-methoxy-6- (3-morpholine-4-ylpropyloxy) quinazoline-4 (3H) - one 7-Methoxy-6-(3-morpholinopropoxy)quizolin-4(3H)-one 7-methoxy-6-(4-morpholinobutyl) quinazolin-4(3H)-one 199327-61-2 31936 Gefitinib INTERMEDIATES Heterocycles Intermediates Intermediates & Fine Chemicals Pharmaceuticals