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cinnabarinic acid

cinnabarinic acid Structure
CAS No.
606-59-7
Chemical Name:
cinnabarinic acid
Synonyms
Cinnabaric Acid;cinnabarinic acid;*Halothane Impurity 5 (Halothane EP Impurity E);2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid;3H-Phenoxazine-1,9-dicarboxylic acid, 2-amino-3-oxo-
CBNumber:
CB31312499
Molecular Formula:
C14H8N2O6
Molecular Weight:
300.22
MOL File:
606-59-7.mol
Modify Date:
2023/6/30 15:45:59
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cinnabarinic acid Properties

Melting point >300°C
Density 1.79
storage temp. 2-8°C
solubility DMSO: ≥4mg/mL
form powder
color red to very dark red
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3

cinnabarinic acid price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0096 Cinnabarinic Acid ≥98% (HPLC) 606-59-7 5MG ₹13303.93 2022-06-14 Buy
Sigma-Aldrich(India) SML0096 Cinnabarinic Acid ≥98% (HPLC) 606-59-7 25MG ₹53334.78 2022-06-14 Buy
Product number Packaging Price Buy
SML0096 5MG ₹13303.93 Buy
SML0096 25MG ₹53334.78 Buy

cinnabarinic acid Chemical Properties,Uses,Production

Description

Cinnabarinic acid is a phenoxazinone produced by the oxidative dimerization of 3-hydroxyanthranilic acid (3-HAA) as part of the metabolism of tryptophan in the kynurenic pathway. It acts as a partial receptor agonist of the metabotropic glutamate receptor 4 (mGlu4), effective at 100 μM, with no activity at other mGlu receptor subtypes. 3-HAA does not affect mGlu receptors, including mGlu4. Cinnabarinic acid induces apoptosis of T cells at 300-500 μM, a potency some ten times that of 3-HAA.

Chemical Properties

Dark Red Solid

Uses

A natural phenoxazinone derivative, Cinnabarinic acid is obtained in vitro with aid of laccase by oxidative dimerization of 3-Hydroxyanthranilic acid (a metabolite of the amino acid Trytophan). Cinnabarinic acid strongly induces apoptosis in thymocytes through the generation of reactive oxygen species and the induction of caspase.

cinnabarinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

cinnabarinic acid Suppliers

Global( 46)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9626 58 Inquiry
ZHEJIANG JIUZHOU CHEM CO., LTD +86-0576225566889 +86-13454675544 China 19947 58 Inquiry
Finetech Industry Limited 027-87465837 19945049750 China 9625 58 Inquiry
JiangSu Star Science Co.,Ltd 400-605-7200 17312445705 China 3764 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
LGC Science (Shanghai) Ltd. 17717235263 China 11572 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 China 29803 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Finetech Industry Limited 58
ZHEJIANG JIUZHOU CHEM CO., LTD 58
Finetech Industry Limited 58
JiangSu Star Science Co.,Ltd 58
Cayman Chemical Company 81
Shanghai EFE Biological Technology Co., Ltd. 58
LGC Science (Shanghai) Ltd. 58
BOC Sciences 65
Shanghai Maclean Biochemical Technology Co., LTD 58

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cinnabarinic acid 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid Cinnabaric Acid 3H-Phenoxazine-1,9-dicarboxylic acid, 2-amino-3-oxo- *Halothane Impurity 5 (Halothane EP Impurity E) 606-59-7 Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals