violacein

violacein Structure
CAS No.
548-54-9
Chemical Name:
violacein
Synonyms
Anorosin;violacein;Brn 0049923;Violacein from Janthinobacterium lividum;3-(2-(5-Hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)-2-indolinone;2-Indolinone, 3-(2-(5-hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)-;Oxindole, 3-(2-(5-hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)- (6ci);3-[2-(5-Hydroxy-1H-indol-3-yl)-5-oxo-2-pyrrolin-4-ylidene]-2-indolinone;3-[2-(5-Hydroxy-1H-indol-3-yl)-5-oxo-2-pyrrolin-4-ylidene]-1,3-dihydro-2H-indol-2-one;3-[5-(5-Hydroxy-1H-indole-3-yl)-2,3-dihydro-2-oxo-1H-pyrrole-3-ylidene]-1H-indole-2(2H)-one
CBNumber:
CB31385284
Molecular Formula:
C20H13N3O3
Molecular Weight:
343.34
MOL File:
548-54-9.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:05

violacein Properties

Melting point >350 °C (decomp)
Boiling point 821.4±65.0 °C(Predicted)
Density 1.549±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: insoluble
form A solid
pka 9.72±0.40(Predicted)
color Brown to black

SAFETY

Risk and Safety Statements

WGK Germany  3

violacein price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) V9389 Violacein from Janthinobacterium lividum >98% (violacein (minimum 85% violacein) and deoxyviolacein, HPLC) 548-54-9 1MG ₹39338.05 2022-06-14 Buy
Product number Packaging Price Buy
V9389 1MG ₹39338.05 Buy

violacein Chemical Properties,Uses,Production

Description

Violacein is a naturally occurring di-indole-pyrrole violet-blue colored pigment that possesses numerous biological functions such as antimicrobial, antiviral, anticancer, antiulcerogenic, anti-leishmanial, and enzyme modulation properties (Narsing et al. 2017). Violacein is biosynthesized by bacterial species such as Chromobacterium violaceum, Collimonas sp., Pseudoalteromonas sp., Pseudomonas aeruginosa, and Janthinobacterium sp. This natural pigment is used extensively in the cosmetic, food, pharmaceutical, and textile industries (Baiano 2014).

Uses

Violacein is an intense violet pigment formed by the condensation of two tryptophan units, found in a number of bacteria, notably Chromobacterium violaceum. The regulation of pigment biosynthesis is the chromogenic basis for the use of C. violaceum CV26 for the detection of quorum sensing mediators. Violacein exhibits broad spectrum actvity against bacteria, protozoans (including malaria), viruses and mammalian cell lines. Violacein cell toxicity resembles TNF-α signal transduction.

Definition

ChEBI: violacein is a member of the class of hydroxyindoles resulting from the formal oxidative coupling between the 3-position of 1,3-dihydro-2H-indol-2-one and the 3-position of 1,3-dihydro-2H-pyrrol-2-one, which is substituted at the 5 position by a 5-hydroxy-1H-indol-3-yl group, where the newly-formed double bond has E configuration. It is a purple chromobacterial pigment that has antibacterial, antifungal, antiprotozoan, and anticancer properties.

General Description

Violacein from Janthinobacterium lividum is used as a colorant for natural and synthetic fabrics. It functions as a respiratory pigment and regulates tryptophan production. Violacein exhibits anti-protozoal activity.

violacein Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 22)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569266 15319487004 China 4088 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Shaanxi Didu New Material Co., Ltd 029-63373950 15353716720 China 10011 58 Inquiry
Zibo Biopolar Rongchuang Pharmaceutical Co. Ltd. 0533-6092686 13371592196 China 1610 58 Inquiry
Naturewill Biotechnology Co., Ltd. 18113192475 18113192475 China 4999 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28091 58 Inquiry
Alfa Chemistry 1-516-6625404 United States 9171 60 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
violacein 3-[2-(5-Hydroxy-1H-indol-3-yl)-5-oxo-2-pyrrolin-4-ylidene]-1,3-dihydro-2H-indol-2-one 3-[2-(5-Hydroxy-1H-indol-3-yl)-5-oxo-2-pyrrolin-4-ylidene]-2-indolinone 3-[5-(5-Hydroxy-1H-indole-3-yl)-2,3-dihydro-2-oxo-1H-pyrrole-3-ylidene]-1H-indole-2(2H)-one 2-Indolinone, 3-(2-(5-hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)- 3-(2-(5-Hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)-2-indolinone Brn 0049923 Oxindole, 3-(2-(5-hydroxyindol-3-yl)-5-oxo-2-pyrrolin-4-ylidene)- (6ci) Anorosin Violacein from Janthinobacterium lividum 2H-Indol-2-one, 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-, (3E)- 548-54-9