Allantoin
- CAS No.
- 97-59-6
- Chemical Name:
- Allantoin
- Synonyms
- ALL;Allatoin;GLYOXYLDIUREIDE;5-UREIDOHYDANTOIN;ALANTOIN;Egopsoryl;GLYOXYLIDIUREIDE;N-(2,5-Dioxo-4-imidazolidinyl)urea;toin;nsc7606
- CBNumber:
- CB3215461
- Molecular Formula:
- C4H6N4O3
- Molecular Weight:
- 158.12
- MOL File:
- 97-59-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
Melting point | 230 °C (dec.) (lit.) |
---|---|
Boiling point | 283.17°C (rough estimate) |
Density | 1.6031 (rough estimate) |
refractive index | 1.8500 (estimate) |
Flash point | 230-234°C |
storage temp. | 2-8°C |
solubility | H2O: soluble0.1g/10 mL, clear, colorless |
form | Powder |
pka | 8.96(at 25℃) |
color | White |
Odor | odorless, tasteless |
Water Solubility | Slightly soluble in water. Freely soluble in alkalis |
Decomposition | 230-234 ºC |
Merck | 14,258 |
BRN | 102364 |
Stability | Stable. Incompatible with strong oxidizing agents. |
InChIKey | POJWUDADGALRAB-UHFFFAOYSA-N |
LogP | -2.26 at 20℃ |
CAS DataBase Reference | 97-59-6(CAS DataBase Reference) |
NIST Chemistry Reference | Urea, (2,5-dioxo-4-imidazolidinyl)-(97-59-6) |
EPA Substance Registry System | Allantoin (97-59-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-36/37/38 | |||||||||
Safety Statements | 22-24/25-36-26 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | YT1600000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29332100 | |||||||||
NFPA 704 |
|
Allantoin price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | PHR1364 | Allantoin Pharmaceutical Secondary Standard; Certified Reference Material | 97-59-6 | 500MG | ₹9894.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 93791 | Allantoin analytical standard | 97-59-6 | 50MG | ₹9601.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 05670 | Allantoin ≥98.0% (N) | 97-59-6 | 25G | ₹2381.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 05670 | Allantoin ≥98.0% (N) | 97-59-6 | 100G | ₹3420.7 | 2022-06-14 | Buy |
TCI Chemicals (India) | A0211 | Allantoin | 97-59-6 | 25G | ₹1800 | 2022-05-26 | Buy |
Allantoin Chemical Properties,Uses,Production
Description
Allantoin is a product of purine and uric acid metabolism. It is formed through oxidation of uric acid by urate oxidase in most mammals but is formed only through non-enzymatic oxidation by free radicals in humans. Urinary levels of allantoin are increased prior to the onset of Alzheimer’s disease symptoms in mice expressing mutations in amyloid precursor protein and tau (APP/tau) but not during the early/middle stage of the disease, indicating its potential use as a biomarker for predicting Alzheimer’s disease onset. Due to the formation of allantoin by free radicals in humans, increased urinary levels are a potential biomarker for oxidative stress status.
Chemical Properties
White Solid
Uses
allantoin is a botanical extract said to be healing, calming, and soothing, it can also help protect the skin from harmful external factors (e.g., wind burn). It is considered an excellent temporary anti-irritant and is believed to stimulate new tissue growth, helping heal damaged skin. Allantoin is appropriate for sensitive, irritated, and acne skins. Derived from the comfrey root, it is considered non-allergenic.
Definition
ChEBI: An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen.
General Description
Allantoin, the final catabolic product of purines in mammals, is a highly polar and amphoteric substance. Allantoin is mainly used for skin protection as the drug promotes cell proliferation and wound healing.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Purification Methods
It crystallises from water or EtOH [Hartman et al. Org Synth Coll Vol II 21 1943]. [Beilstein 25 III/IV 4071.]
Allantoin Preparation Products And Raw materials
Raw materials
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Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Laksh Finechem Pvt.Ltd. | +91-9978522233 +91-78522233 | Gujarat, India | 55 | 58 | Inquiry |
SNA HEALTHCARE PVT LTD | +91-8652842416 +91-8652842416 | Mumbai, India | 88 | 58 | Inquiry |
PERFECT CHEMICAL | +91-9820465461 +91-9820465461 | Mumbai, India | 391 | 58 | Inquiry |
AVD pharmaceuticals Pvt Ltd | +919860835260 | Pune, India | 102 | 58 | Inquiry |
Murli Krishna Exports Pvt Ltd | +91-2225631595 +91-2225631594 | New Delhi, India | 185 | 58 | Inquiry |
Salicylates and Chemicals Pvt. Ltd. | +91-8879630551 +91-8898005838 | Maharashtra, India | 61 | 58 | Inquiry |
KIP Chemicals Pvt Ltd | +91 8657441706, +91 9167110259 | Maharashtra, India | 3 | 58 | Inquiry |
Ester India | +91-2652840442 +91-9898872338 | Telangana, India | 4 | 58 | Inquiry |
Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
Monachem Specialities LLP | +91-0265-2966227 +91-02652966227 | Gujarat, India | 35 | 58 | Inquiry |
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