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Allantoin

Allantoin Structure
CAS No.
97-59-6
Chemical Name:
Allantoin
Synonyms
ALL;Allatoin;GLYOXYLDIUREIDE;5-UREIDOHYDANTOIN;ALANTOIN;Egopsoryl;GLYOXYLIDIUREIDE;N-(2,5-Dioxo-4-imidazolidinyl)urea;toin;nsc7606
CBNumber:
CB3215461
Molecular Formula:
C4H6N4O3
Molecular Weight:
158.12
MOL File:
97-59-6.mol
MSDS File:
SDS
Modify Date:
2024/7/25 20:04:51

Allantoin Properties

Melting point 230 °C (dec.) (lit.)
Boiling point 283.17°C (rough estimate)
Density 1.6031 (rough estimate)
refractive index 1.8500 (estimate)
Flash point 230-234°C
storage temp. 2-8°C
solubility H2O: soluble0.1g/10 mL, clear, colorless
form Powder
pka 8.96(at 25℃)
color White
Odor odorless, tasteless
Water Solubility Slightly soluble in water. Freely soluble in alkalis
Decomposition 230-234 ºC
Merck 14,258
BRN 102364
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey POJWUDADGALRAB-UHFFFAOYSA-N
LogP -2.26 at 20℃
CAS DataBase Reference 97-59-6(CAS DataBase Reference)
NIST Chemistry Reference Urea, (2,5-dioxo-4-imidazolidinyl)-(97-59-6)
EPA Substance Registry System Allantoin (97-59-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  1
RTECS  YT1600000
TSCA  Yes
HS Code  29332100
NFPA 704
0
1 0

Allantoin price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1364 Allantoin Pharmaceutical Secondary Standard; Certified Reference Material 97-59-6 500MG ₹9894.05 2022-06-14 Buy
Sigma-Aldrich(India) 93791 Allantoin analytical standard 97-59-6 50MG ₹9601.78 2022-06-14 Buy
Sigma-Aldrich(India) 05670 Allantoin ≥98.0% (N) 97-59-6 25G ₹2381.5 2022-06-14 Buy
Sigma-Aldrich(India) 05670 Allantoin ≥98.0% (N) 97-59-6 100G ₹3420.7 2022-06-14 Buy
TCI Chemicals (India) A0211 Allantoin 97-59-6 25G ₹1800 2022-05-26 Buy
Product number Packaging Price Buy
PHR1364 500MG ₹9894.05 Buy
93791 50MG ₹9601.78 Buy
05670 25G ₹2381.5 Buy
05670 100G ₹3420.7 Buy
A0211 25G ₹1800 Buy

Allantoin Chemical Properties,Uses,Production

Description

Allantoin is a product of purine and uric acid metabolism. It is formed through oxidation of uric acid by urate oxidase in most mammals but is formed only through non-enzymatic oxidation by free radicals in humans. Urinary levels of allantoin are increased prior to the onset of Alzheimer’s disease symptoms in mice expressing mutations in amyloid precursor protein and tau (APP/tau) but not during the early/middle stage of the disease, indicating its potential use as a biomarker for predicting Alzheimer’s disease onset. Due to the formation of allantoin by free radicals in humans, increased urinary levels are a potential biomarker for oxidative stress status.

Chemical Properties

White Solid

Uses

allantoin is a botanical extract said to be healing, calming, and soothing, it can also help protect the skin from harmful external factors (e.g., wind burn). It is considered an excellent temporary anti-irritant and is believed to stimulate new tissue growth, helping heal damaged skin. Allantoin is appropriate for sensitive, irritated, and acne skins. Derived from the comfrey root, it is considered non-allergenic.

Definition

ChEBI: An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen.

General Description

Allantoin, the final catabolic product of purines in mammals, is a highly polar and amphoteric substance. Allantoin is mainly used for skin protection as the drug promotes cell proliferation and wound healing.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Purification Methods

It crystallises from water or EtOH [Hartman et al. Org Synth Coll Vol II 21 1943]. [Beilstein 25 III/IV 4071.]

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(2,5-dioxo-4-imidazolidinyl)urea ALLANTOIN Alphosyl Alyonyldiurened Allantin CORDIANINE Allantoin,98% 1-(2,5-Dioxoimidazolidin-4-yl)-urea Allantoin (200 mg) Allantoin, USP, EP 5-Ureidohydantoin, Glyoxylic(acid) diureide [(4R)-2,5-dioxoiMidazolidin-4-yl]urea Allantoin, 98% 100GR Allantoin skin curative Allantoi glyoxylic diureide GLYOXYLIC ACID DIUREIDE glyoxyldiureid LABOTEST-BB LT02085084 TIMTEC-BB SBB003997 UREA, (2,5-DIOXO-4-IMIDAZOLIDINYL) Hydantoin, 5-ureido- nsc7606 Psoralon Sebical Septalan toin uniderma (2,5-Dioxo-imidazolidin-4-yl)-urea AllantoinPowder ALLANTOIN POWDER ( Glyoxylic acid Diureide) Allantoin >=98.0% (N) AllantoinuM Alantan、Allegron、Alphosyl、Alyonyldiurened、Cordianine、Egopsoryl、Sebical Urea, N-(2,5-dioxo-4-imidazolidinyl)- AllantoinUSP, 98.5-101.0% (Assay) (2,5-Dioxo-4-imidazolidinyl)urea 5-Ureidohydantoin Glyoxyldiureide Cordianine ALLANTOIN (5-UREIDOHYDANTOIN) Allantoine ( 2,5-Dioxo-4-imidazoidinyl urea) 5-ureido-hydantoi 5-Ureidohydrantoin ai3-15281 Alantan Allantol AVC/Dienestrolcream component of Skin-balm Fancol TOIN 5-ureidohydantoin (2,5-dioxoimidazolidin-4-yl)urea ALLANTOIN(RG) 2,5-DIOXO-4-IMIDAZOLIDINYLUREA(ALLANTOIN) (2,5-dioxo-4-imidazolidinyl)-ure 2,5-Dioxo-4-imidazolidinylarea 2,5-Imidazolidinedione, 4-ureido- Allantoin Joyce Allantoin CRS Allantoin > Allantoin Standard Allantoin USP/EP/BP