7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one

7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one Structure
CAS No.
193686-76-9
Chemical Name:
7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
Synonyms
Tovaptan impurity 4;Tolvaptan Impurity 24;7-chloro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one;7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one;7-chloro-5-oxo-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1...;7-Chloro-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-benzo[b]azepin-5-one;7-chloro-5-oxo-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine;7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one;5H-1-Benzazepin-5-one, 7-chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-;7-Chloro-1-(4-Mechirubenzensuruhoniru)-2,3,4,5-tetrahydro-1H-benzo [b] azepine 5-one
CBNumber:
CB32510120
Molecular Formula:
C17H16ClNO3S
Molecular Weight:
349.83
MOL File:
193686-76-9.mol
Modify Date:
2023/7/21 8:27:57

7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one Properties

Boiling point 536.5±60.0 °C(Predicted)
Density 1.36
pka -4.58±0.20(Predicted)

7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one Chemical Properties,Uses,Production

Uses

7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one is used as a reactant in the asymetric preparation of an intermediate in the synthesis of both enantiomers of Tolvaptan (T536650).

7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one Preparation Products And Raw materials

Raw materials

Preparation Products

7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one Suppliers

7-Chloro-1-(4-Mechirubenzensuruhoniru)-2,3,4,5-tetrahydro-1H-benzo [b] azepine 5-one 7-Chloro-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-benzo[b]azepin-5-one 7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one 5H-1-Benzazepin-5-one, 7-chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]- 7-Chloro-1-tosyl-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one 7-chloro-5-oxo-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1... 7-chloro-1-tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one Tolvaptan Impurity 24 7-chloro-5-oxo-1-(p-toluenesulfonyl)-2,3,4,5-tetrahydro-1H-1-benzazepine Tovaptan impurity 4 7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl) -2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl 2-methylbenzoate 193686-76-9