NSC 23766 (hydrochloride)
- CAS No.
- 1177865-17-6
- Chemical Name:
- NSC 23766 (hydrochloride)
- Synonyms
- NSC-23766 HCl;Rac1 Inhibitor;NSC-23766 3HCl;NSC 23766, >=98%;NSC23766 trihydrochloride;NSC 23766 (hydrochloride);NSC-23766 trihydrochloride;NSC 23766 (trihydrochloride);NSC 23766;NSC23766;NSC-23766;NSC 23766 (hydrochloride) USP/EP/BP
- CBNumber:
- CB32591873
- Molecular Formula:
- C24H35N7
- Molecular Weight:
- 421.5816
- MOL File:
- 1177865-17-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
NSC 23766 (hydrochloride) price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0952 | NSC23766 trihydrochloride ≥97% (HPLC) | 1177865-17-6 | 5MG | ₹14152.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0952 | NSC23766 trihydrochloride ≥97% (HPLC) | 1177865-17-6 | 25MG | ₹56898.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 553502 | Rac1 Inhibitor - CAS 1177865-17-6 - Calbiochem Rac1 Inhibitor, CAS 1177865-17-6, is a cell-permeable, reversible inhibitor of Rac1 GDP/GTP exchange. Interferes with the interaction between Rac1 and | 1177865-17-6 | 5MG | ₹35820.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 553502 | Rac1 Inhibitor - CAS 1177865-17-6 - Calbiochem Rac1 Inhibitor, CAS 1177865-17-6, is a cell-permeable, reversible inhibitor of Rac1 GDP/GTP exchange. Interferes with the interaction between Rac1 and | 1177865-17-6 | 10MG | ₹44200.01 | 2022-06-14 | Buy |
NSC 23766 (hydrochloride) Chemical Properties,Uses,Production
Description
Rac1 is a GTPase that is involved in the regulation of the cell cycle, cell-
Uses
NSC 23766 is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
Biochem/physiol Actions
NSC23766 is an inhibitor of Rac1, a Rho-family GTPase. The compound blocks activation by the guanine nucleotide exchange factors Trio and Tiam1, but does not affect interactions with RhoA or Cdc42. NSC23766 blocks ADP-mediated platelet aggregation. Inhibition of Rac1 by NSC23766 restores sensitivity to trastuzumab by restoring down-regulation of ErbB2.
NSC 23766 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 22854 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10473 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6391 | 58 | Inquiry |
| TargetMol Chemicals Inc. | United States | 38630 | 58 | Inquiry | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
| Aladdin Scientific | United States | 57505 | 58 | Inquiry |