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LY 294002 HYDROCHLORIDE

CAS No.: 154447-36-6

Chemical Name:: LY 294002 HYDROCHLORIDE

Synonyms: YX;SF 1101;CS-1859;LY240092;LY 294002;NSC 697286;LY294002HCl;LY294002/PI3K;LY 294002, 99+%;PI3K inhibitor kit

CBNumber:: CB1242450

Molecular Formula:: C19H17NO3

Molecular Weight:: 307.34

MOL File:: 154447-36-6.mol

MSDS File:: SDS

Modify Date:: 2023/5/18 11:31:15

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LY 294002 HYDROCHLORIDE Properties

Melting point	183-185℃
Boiling point	494.6±45.0 °C(Predicted)
Density	1.266
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMSO: >5 mg/mL
form	solid
pka	0.55±0.20(Predicted)
color	white to off-white
Water Solubility	Soluble in DMSO at 5mg/ml. Insoluble in water
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
InChIKey	CZQHHVNHHHRRDU-UHFFFAOYSA-N
CAS DataBase Reference	154447-36-6

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H302-H320-H361-H370-H372-H336-H402
Precautionary statements	P501-P273-P260-P270-P202-P201-P271-P264-P280-P337+P313-P305+P351+P338-P308+P311-P301+P312+P330-P304+P340+P312-P403+P233-P405
Safety Statements	24-25
WGK Germany	3
HS Code	29349990

LY 294002 HYDROCHLORIDE price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	440202	LY 294002 - CAS 154447-36-6 - Calbiochem LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC?? = 1.4 μM). Acts on the ATP-binding si	154447-36-6	5MG	₹22429.99	2022-06-14	Buy
Sigma-Aldrich(India)	440202	LY 294002 - CAS 154447-36-6 - Calbiochem LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC?? = 1.4 μM). Acts on the ATP-binding si	154447-36-6	10MG	₹30100	2022-06-14	Buy
Sigma-Aldrich(India)	440204	InSolution LY 294002 - CAS 154447-36-6 - Calbiochem InSolution LY 294002, CAS 154447-36-6, is a 10 mM solution of LY 294002 (Cat. No. 440202) in DMSO. A cell-permeable, potent, reversible and specific i	154447-36-6	1MG	₹10660	2022-06-14	Buy
Sigma-Aldrich(India)	440202	LY 294002 - CAS 154447-36-6 - Calbiochem LY294002, CAS 154447-36-6, is a cell-permeable, potent, reversible, and specific inhibitor of PI 3-kinase ((IC?? = 1.4 μM). Acts on the ATP-binding si	154447-36-6	25MG	₹37350	2022-06-14	Buy
Sigma-Aldrich(India)	19-142	LY 294002	154447-36-6	1MG	₹16610	2022-06-14	Buy

Product number	Packaging	Price	Buy
440202	5MG	₹22429.99	Buy
440202	10MG	₹30100	Buy
440204	1MG	₹10660	Buy
440202	25MG	₹37350	Buy
19-142	1MG	₹16610	Buy

LY 294002 HYDROCHLORIDE Chemical Properties,Uses,Production

Description

LY294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor with a 2.7-fold greater potency than quercetin. LY294002 inhibits purified PI3K with an IC₅₀ of 1.4 μM.

Uses

A potent blocker of PI 3-kinase/Akt signaling.

Definition

ChEBI: A chromone substituted with a phenyl group at position 8 and a morpholine group at position 2.

Biological Activity

A highly selective inhibitor of phosphatidylinositol 3-kinase (IC 50 values are 0.31, 0.73, 1.06 and 6.60 μ M for PI3K β , PI3K α , PI3K δ and PI3K γ respectively). Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo .

LY 294002 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

4H-1-Benzopyran-4-one, 8-hydroxy-2-(4-morpholinyl)- 1-(2-hydroxybiphenyl-3-yl)-3-morpholinopropane-1,3-dione N-Acetylmorpholine Trifluoro-methanesulfonic acid 2-morpholin-4-yl-4-oxo-4H-chromen-8-yl ester methyl 2-hydroxy-3-phenyl-benzoate

methyl 2,3-dihydroxybenzoate Methyl 3-methoxysalicylate 2,3-Dihydroxybenzoic acid 3-Methoxysalicylic acid Phenylboronic acid

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Preparation Products

LY 294002 HYDROCHLORIDE Suppliers

Global( 292)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29898	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Xi'an MC Biotech, Co., Ltd.	029-89275612 +8618991951683	China	2255	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
TCI Chemicals (India) Pvt. Ltd.	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Xi'an MC Biotech, Co., Ltd.	58

LY 294002 HYDROCHLORIDE Spectrum

LY 294002 HYDROCHLORIDE(154447-36-6)¹HNMR

154447-36-6(LY 294002 HYDROCHLORIDE)Related Search:

NAD+ Ribonucleic acid Acetylcholine 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 (S)-3-fluoro-4-(4-((2-(3-fluorophenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide LY 88074 LY-364947 LY2409881 trihydrochloride

LY 2784544 LY2584702 LY3214996 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol Etalocib

LY2228820 LY-2562175 LY2828360

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LY 294002 LY 294002 HYDROCHLORIDE 2-[4-MORPHOLINYL]-8-PHENYL-1[4H]-BENZOPYRAN-4-ONE 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE HYDROCHLORIDE 2-(4-MORPHOLINO)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE LY 294002, 99+% LY294002HCl 2-(4-morpholinyl)-8-phenyl-1(4h)-benzopyran-4-one hydrochloride LY-294002;LY 294002;LY 294002 HYDROCHLORIDE;2-[4-MORPHOLINYL]-8-PHENYL-1[4H]-BENZOPYRAN-4-ONE;2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE;2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE HYDROCHLORIDE;2-(4-MORPHOLINO)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE 8-Phenyl-2-(morpholin-4-yl)chromen-4-one 2-[4-Morpholinyl]-8-phenyl-1[4H]-benzopyran-4-on NSC 697286 SF 1101 2-Morpholino-8-phenyl-4H-chroMen-4-one 2-Morpholino-8-phenylchroMone 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one LY 294002 LY 294002 8-Phenyl-2-(morpholin-4-yl)chromen-4-one LY294002 (HCI Salt) LY240092 LY294002, NSC 697286 2-Morpholino-8-phenyl-4-oxo-4H-1-benzopyran InSolution? LY 294002 CS-1859 LY294002 (HCl Salt) 2-(4-MORPHOLINO)-8-PHENYL-4H-1-BENZOPYRAN-4-ON InSolution LY 294002 - CAS 154447-36-6 - Calbiochem LY 294002 - CAS 154447-36-6 - Calbiochem 2-(4-Morpholinyl)-8-phenyl-4H-chromen-4-on PI3K inhibitor kit NSC 697286; SF 1101; LY 294002; LY-294002 Morpholino phenylchromone 2-Morpholino-8-phenylchromone> 4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl- YX LY294002/PI3K LY 294002 HYDROCHLORIDE USP/EP/BP LY 294002, Free Base LY 294002 (DMSO solution) 154447-36-6 C19H18ClNO3HCl C19H17O3N Specific cell permeable phosphatidylinositol 3-kinase inhibitor. Cell Biology Cell Signaling and Neuroscience BioChemical Kinase/Phosphatase Biology Phosphatidylinositol 3-kinase (PI3K) Serine/Threonine Kinase Inhibitors Inhibitors Inhibitor Anti-cancer&immunity PI3K/Akt/mTOR Akt mTOR PI3K Cell Cycle Regulation apis