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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Mitogen-activated protein kinase (MAPK) >p38 MAPK inhibitor >LY2228820

LY2228820

LY2228820 Structure
CAS No.
862507-23-1
Chemical Name:
LY2228820
Synonyms
CS-371;LY2228820;LY2228820 2MsOH;Ralimetinib 2MsOH;LY2228820 USP/EP/BP;LY2228820 diMesylate;LY2228820 (mesylate);Ralimetinib Mesylate;LY2228820(LY-2228820);LY2228820 (Ralimetinib)
CBNumber:
CB82518277
Molecular Formula:
C26H37FN6O6S2
Molecular Weight:
612.7369832
MOL File:
862507-23-1.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:20
Request For Quotation

LY2228820 Properties

storage temp. Store at -20°C
solubility ≥30.65 mg/mL in DMSO; ≥45 mg/mL in H2O with ultrasonic; ≥9.9 mg/mL in EtOH with ultrasonic
form solid
color White to yellow

SAFETY

Risk and Safety Statements

HS Code  2933998090

LY2228820 Chemical Properties,Uses,Production

Uses

LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. LY2228820 significantly inhibited phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, in both multiple myeloma (MM) cell lines and LT-BMSCs. LY2228820 is a potential candidate to improve MM patient outcome both by enhancing the effect of Bortezomib (B675700) and by reducing osteoskeletal events.

LY2228820 Preparation Products And Raw materials

Raw materials

Preparation Products

LY2228820 Suppliers

Global( 107)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
SUZHOU SENFEIDA CHEMICAL CO.,LTD +86-0512-83500002 +8615195660023 China 23053 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Capot Chemical Co.,Ltd. 60
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
career henan chemical co 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
TargetMol Chemicals Inc. 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD 58

LY2228820 Spectrum

LY2228820(862507-23-1)1HNMR

862507-23-1(LY2228820)Related Search:

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5-(2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate 5-(2-(tert-butyl)-5-(4-fluorophenyl)-1H-imidazol-4-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate LY2228820;LY 2228820;LY-2228820 5-(2-tert-Butyl-5-(4-fluorophenyl)-1H-imidazol-4-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-am LY2228820 5-[2-(1,1-DiMethylethyl)-5-(4-fluorophenyl)-1H-iMidazol-4-yl]-3-(2,2-diMethylpropyl)-3H-iMidazo[4,5-b]pyridin-2-aMine DiMethanesulfonate LY2228820(LY-2228820) LY2228820 2MsOH LY2228820 diMesylate 5-[2-(tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate LY2228820 (Ralimetinib) dimesylate LY2228820 (mesylate) Ralimetinib Mesylate RALIMETINIB DIMESYLATE (LY2228820 DIMESYLATE) Ralimetinib 2MsOH(LY2228820) CS-371 LY2228820 (Ralimetinib) RALIMETINIB DIMESYLATE; LY2228820 DIMESYLATE; LY2228820 2MSOH; LY 2228820; LY-2228820 Ralimetinib 2MsOH LY2228820 USP/EP/BP Ralimetinib dimysylate (LY2228820 dimysylate) Ralimetinib mesylate LY2228820 LY-2228820 862507-23-1 C24H29FN62CH4O3S C25H33FN6O3S C26H37FN6O6S2 Inhibitors Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators MAPK