LY2228820
LY2228820
- CAS:
- 862507-23-1
- MF:
- C26H37FN6O6S2
- MW:
- 612.7369832
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Properties
- storage temp.
- Store at -20°C
- solubility
- ≥30.65 mg/mL in DMSO; ≥45 mg/mL in H2O with ultrasonic; ≥9.9 mg/mL in EtOH with ultrasonic
- form
- solid
- color
- White to yellow
Safety Information
- HS Code
- 2933998090
Use
LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. LY2228820 significantly inhibited phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, in both multiple myeloma (MM) cell lines and LT-BMSCs. LY2228820 is a potential candidate to improve MM patient outcome both by enhancing the effect of Bortezomib (B675700) and by reducing osteoskeletal events.
1 India supplier list of "LY2228820"