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SB 203580

SB 203580

CAS:
152121-47-6
MF:
C21H16FN3OS
MW:
377.43

Properties

Melting point:
144-146
Boiling point:
615.6±55.0 °C(Predicted)
Density 
1.4
storage temp. 
-20°C
solubility 
DMSO: 50 mg/mL
form 
solid
pka
9.60±0.10(Predicted)
color 
white to off-white
Stability:
-200C
InChIKey
CDMGBJANTYXAIV-UHFFFAOYSA-N

Safety Information

Symbol(GHS) 

GHS05,GHS07
Signal word 
Danger
Hazard statements 
H302-H318
Precautionary statements 
P264-P270-P280-P301+P312-P305+P351+P338-P501
Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26-39
WGK Germany 
3
HS Code 
29333990

Use

Water-soluble salt of SB 203580 (4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine ). Selective inhibitor of p38 mitogen-activated protein kinase (IC 50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38 2 respectively). Displays 100-500-fold selectivity over LCK, GSK3 and PKB . Shown to inhibit interleukin-2-induced T-cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.

1 India supplier list of "SB 203580"

  • Product Name:SB203580
  • Products Intro:Brand:sigma aldrich | Product Number:S8307 | Purity:solid,≥98%(HPLC)
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:SB203580 >95%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.089121
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:SB-203580
  • Products Intro:Brand:ajchemicals | Product Number:JDH-36268 | Purity:98+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:SB-203580
  • Products Intro:Brand:clearsynth | Product Number:CS-T-42140
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:SB203580
  • Products Intro:Brand:tcichemicals | Product Number:F0864
  • Company Type: Reagent
  • Country/Region: New Delhi,INDIA
  • Product Name:SB203580,≥98%(HPLC)
  • Products Intro:Brand:ottokemi | Product Number:S0844 | Purity:98%
  • Company Type: Trader
  • Country/Region: Mumbai,INDIA
  • Product Name:SB 2035850
  • Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
  • Product Name:4-(4-FLUOROPHENYL)-2-(4-METHYLSULFINYLPHENYL)-5-(4-PYRIDYL) 1H-IMIDAZOLE
  • Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:SB 203580
  • Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
  • Company Type: Reagent
  • Country/Region: CHINA
  • Product Name:SB-203580
  • Products Intro:Purity: >98% | Package: 1g | CustNote: BOC Sciences also provides custom synthesis services for SB-203580.
  • Company Type: Trader
  • Country/Region: UNITED STATES

SB 203580 Related Search:

SB 202190SB 4315425-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oximeSB13176-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline4'-CHLORO-3-METHOXYCINNAMANILIDESB-705498SB2422352-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochlorideIspinesibMK-2206 2HCl1,9-PyrazoloanthronePD 98059SCH772984LY 294002 HYDROCHLORIDEMMP-2/MMP-9 INHIBITOR IVSB 415286Sb-742457
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