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Y27632 (hydrochloride)

CAS No.: 129830-38-2

Chemical Name:: Y27632 (hydrochloride)

Synonyms: CS-1919;Y27632 HCl;27632 (hydrochloride);Y27632 (hydrochloride);Y-27632; Y27632; Y 27632;Y-27632, Sterile-Filtered;Y-27632 dihydrochloride, >=98%;Y-27632 dihydrochloride Y27632;Y27632 (hydrochloride) USP/EP/BP;Y-27632, Dihydrochloride Salt, >99%

CBNumber:: CB82526054

Molecular Formula:: C14H23Cl2N3O

Molecular Weight:: 320.25792

MOL File:: 129830-38-2.mol

MSDS File:: SDS

Modify Date:: 2025/1/27 9:38:02

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Y27632 (hydrochloride) Properties

Melting point	258℃
storage temp.	2-8°C
solubility	H2O: soluble14mg/mL
form	powder
color	white to beige
optical activity	[α]/D +3.0 to +5.0°, c =1.0 in methanol
biological source	synthetic (organic)
Water Solubility	H2O: 14mg/mL
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332

Precautionary statements

P261-P280-P301+P312+P330

Hazard Codes

Risk Statements

20/21/22

Safety Statements

WGK Germany

HS Code

29333990

NFPA 704

	0
3		0

Y27632 (hydrochloride) price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	Y0503	Y-27632 dihydrochloride ≥98% (HPLC)	129830-38-2	1MG	₹21541.75	2022-06-14	Buy
Sigma-Aldrich(India)	Y0503	Y-27632 dihydrochloride ≥98% (HPLC)	129830-38-2	5MG	₹90886.7	2022-06-14	Buy
TCI Chemicals (India)	Y0018	Y 27632 Dihydrochloride	129830-38-2	50MG	₹14800	2022-05-26	Buy

Product number	Packaging	Price	Buy
Y0503	1MG	₹21541.75	Buy
Y0503	5MG	₹90886.7	Buy
Y0018	50MG	₹14800	Buy

Y27632 (hydrochloride) Chemical Properties,Uses,Production

Uses

A cell permeable inhibitor of ROCK-1 and ROCK-2

General Description

Y-27632 dihydrochloride is an effective bronchodilator and improves lung resistance (RL) induced by antigen and acetylcholine. Y-27632 controls neutrophil migration and lung edema and may be a potential drug for treating acute lung injury.

Biochem/physiol Actions

Y-27632 is highly potent, cell-permeable, selective ROCK (Rho-associated coiled coil forming protein serine/threonine kinase) inhibitor. Ki = 140 nM for p160ROCK. Y-27632 also inhibits ROCK-II with equal potency. The inhibition is competitive with respect to ATP.

Y27632 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

Y27632 (hydrochloride) Suppliers

Global( 181)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6768	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	33024	60	Inquiry
Accela ChemBio Inc.	+1-858-6993322	United States	19825	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19552	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49732	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	22854	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10473	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6391	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3135	58	Inquiry

Supplier	Advantage
TCI Chemicals (India) Pvt. Ltd.	58
ATK CHEMICAL COMPANY LIMITED	60
Accela ChemBio Inc.	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Nantong HI-FUTURE Biology Co., Ltd.	58

Y27632 (hydrochloride) Spectrum

Y27632 (hydrochloride)(129830-38-2)¹HNMR

129830-38-2(Y27632 (hydrochloride))Related Search:

Y-27632 DIHYDROCHLORIDE YC-1 YKP-3089 BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE

Y320 (R)-4-(1-Aminoethyl)-N-1H-pyrrolo[2,3-b]pyridin-4-ylbenzamide (R)-4-(1-aMinoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzaMide dihydrochloride YH239-EE YKL 06-061

YS 49 3-(4-Pyridyl)indole Fasudil hydrochloride SB 431542 PD 0325901

MG-132 CHIR-99021 trans-4-Phenyl-L-proline hydrochloride

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(R)-4-(1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR Y-27632 dihydrochloride, >=98% trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride Y 27632 dihydrochloride Y 27632 dihydrochloride (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride Y27632 (hydrochloride) (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride Y27632 HCl Y-27632, Dihydrochloride Salt, >99% Y-27632; Y27632; Y 27632 CS-1919 Y-27632; Y27632; Y 27632;Y 27632 DIHYDROCHLORIDE;Y27632 DIHYDROCHLORIDE Y-27632 dihydrochloride, 98.5%, a selective ROCK1 (p160ROCK) inhibitor trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride Y27632 (hydrochloride) USP/EP/BP Trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride (Y-27632 dihydrochloride) Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, hydrochloride (1:2), trans- Y-27632 dihydrochloride Y27632 27632 (hydrochloride) Y-27632 dihydrochloride (mM/ml), Rho kinase inhibitor Y-27632, Sterile-Filtered Y-27632 dihydrochloride, Rho kinase inhibitor Y-27632 in solution New Y-27632 dihydrochloride, 10 mM in DMSO 129830-38-2 Inhibitors APIs