ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Mitogen-activated protein kinase (MAPK) >MEK inhibitor >PD 0325901
PD 0325901
- CAS No.
- 391210-10-9
- Chemical Name:
- PD 0325901
- Synonyms
- Mirdametinib;PD325901;Mirdametinib (PD0325901);CS-52;PD 032590;PD 0325901;PD-0235901;PD0325901, >=98%;MEK1/2 Inhibitor III;PD0325901 (PD325901)
- CBNumber:
- CB42464161
- Molecular Formula:
- C16H14F3IN2O4
- Molecular Weight:
- 482.19
- MOL File:
- 391210-10-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 112-114°C |
|---|---|
| Density | 1.817±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble20mg/mL, clear |
| form | White to off-white solid |
| pka | 13.45±0.20(Predicted) |
| color | white to off-white |
| optical activity | [α]/D -1.8 to -3.5°, c = 1 mg/mL in methanol |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| InChIKey | SUDAHWBOROXANE-SECBINFHSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H373-H413 | |||||||||
| Precautionary statements | P260-P264-P270-P273-P301+P310-P314 | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 25-48-50 | |||||||||
| Safety Statements | 22-36/37/39-61 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29242990 | |||||||||
| NFPA 704 |
|
PD 0325901 price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PZ0162 | PD 0325901 ≥98% (HPLC) | 391210-10-9 | 5MG | ₹15891.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PZ0162 | PD 0325901 ≥98% (HPLC) | 391210-10-9 | 25MG | ₹60457.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 444968 | InSolution MEK1/2 Inhibitor III, PD0325901 - CAS 391210-10-9 - Calbiochem The InSolution MEK1/2 Inhibitor III, PD0325901, also referenced under CAS 391210-10-9, controls the biological activity of MEK1/2. This small molecule | 391210-10-9 | 5MG | ₹17860 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 444966 | MEK1/2 Inhibitor III - CAS 391210-10-9 - Calbiochem The MEK1/2 Inhibitor III, also referenced under CAS 391210-10-9, controls the biological activity of MEK1/2. This small molecule/inhibitor is primaril | 391210-10-9 | 5MG | ₹23160 | 2022-06-14 | Buy |
PD 0325901 Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid
Uses
PD 0325901 has been used as an inhibitor in extracellular signal-regulated kinase (ERK) inhibition assay in primed induced pluripotent stem cells, RKO colorectal cancer cell line and human embryonic stem cells(hESCs).
Definition
ChEBI: A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer).
PD 0325901 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 200)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25247 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| changzhou huayang technology co., ltd | +8615250961469 | China | 9827 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
391210-10-9(PD 0325901)Related Search:
N-[(2R)-2,3-DIHYDROXYPROPOXY]-3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]-BENZAMIDE
PD 0325901
(R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide
PD-0235901
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]be
N-[(R)-2,3 -Dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylaMino)-benzaMide
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide PD0325901
PD 0325901
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
PD0325901, >=98%
MEK1/2 Inhibitor III
InSolution? MEK1/2 Inhibitor III, PD0325901
(R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide 98%
PD 0325901; PD325901; PD-0325901
PD0325901(Mirdametinib)
PD0325901 (PD325901)
CS-52
InSolution MEK1/2 Inhibitor III, PD0325901 - CAS 391210-10-9 - Calbiochem
MEK1/2 Inhibitor III - CAS 391210-10-9 - Calbiochem
(870474-62-7) pd 0325901
PD 0325901 USP/EP/BP
PD-325901
DISCONTINUED
PD325901
Mirdametinib
Mirdametinib (PD0325901)
MEK1/2 Inhibitor III PD-0325901 PD0325901 Mirdametinib MEK inhibitor
PD 032590
PD-0325901,MAPKK,Mitogen-activated protein kinase kinase,PD-325901,Apoptosis,PD 0325901,MEK,Autophagy,Mirdametinib,inhibit,PD 325901,MAP2K,Inhibitor
391210-10-9
301210-10-9
C16H14F3IN2O4
MAPK
Inhibitor
Inhibitors
Aromatics
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals
API