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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Angiogenesis >FGFR inhibitor >PD 173074

PD 173074

PD 173074 Structure
CAS No.
219580-11-7
Chemical Name:
PD 173074
Synonyms
CS-458;PD176074;PD-0173074;PD173074, >=98%;PD173074/PD-173074;PD 173074, Free Base;Cholest-5-en-3-ol,(9α)-;PD-173074 FGFR1 FGFR3 inhibitor ab141117;FGF/VEGF Receptor Tyrosine Kinase Inhibitor;FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074
CBNumber:
CB9497090
Molecular Formula:
C28H41N7O3
Molecular Weight:
523.67
MOL File:
219580-11-7.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

PD 173074 Properties

Melting point 82-85°C
Density 1.163
storage temp. 2-8°C
solubility DMSO: 21 mg/mL
form solid
pka 10.12±0.43(Predicted)
color yellow
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280-P271
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  3
HS Code  2933599590
NFPA 704
0
2 0

PD 173074 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P2499 PD 173074 ≥96% (HPLC), powder 219580-11-7 5MG ₹21898.98 2022-06-14 Buy
Sigma-Aldrich(India) P2499 PD 173074 ≥96% (HPLC), powder 219580-11-7 25MG ₹88981.5 2022-06-14 Buy
Sigma-Aldrich 341607 FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 - CAS 219580-11-7 - Calbiochem The FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 controls the biological activity of FGF/VEGF Receptor Tyrosine Kinase. Primarily used for Phosphorylation & Dephosphorylation applications. 219580-11-7 5MG ₹21460 2022-06-14 Buy
Sigma-Aldrich(India) 341607 FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 - CAS 219580-11-7 - Calbiochem The FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 controls the biological activity of FGF/VEGF Receptor Tyrosine Kinase. Primarily used for Ph 219580-11-7 5MG ₹21460 2022-06-14 Buy
TCI Chemicals (India) P2474 PD 173074 219580-11-7 10MG ₹4600 2022-05-26 Buy
Product number Packaging Price Buy
P2499 5MG ₹21898.98 Buy
P2499 25MG ₹88981.5 Buy
341607 5MG ₹21460 Buy
341607 5MG ₹21460 Buy
P2474 10MG ₹4600 Buy

PD 173074 Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

PD 173074 ar signal-related kinase phosphorylation.

Definition

ChEBI: A member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N3 is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at pos tions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor.

Biological Activity

Selective FGFR1 and FGFR3 inhibitor (IC 50 values are 5, 21.5, ~100, 17600 and 19800 nM for FGFR3, FGFR1, VEGFR2, PDGFR and c-Src respectively, and > 50000 nM for EGFR, InsR, MEK and PKC). Inhibits VEGF- and FGF-induced angiogenesis in the mouse cornea model of angiogenesis. Inhibits proliferation and differentiation of oligodendrocyte progenitors.

PD 173074 Preparation Products And Raw materials

Raw materials

Preparation Products

PD 173074 Suppliers

Global( 165)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9337 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
Zhejiang ZETian Fine Chemicals Co. LTD +8618957127338 China 2141 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
TCI Chemicals (India) Pvt. Ltd. 58
Capot Chemical Co.,Ltd. 60
Hangzhou FandaChem Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Zhejiang ZETian Fine Chemicals Co. LTD 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58

PD 173074 Spectrum

PD 173074(219580-11-7)1HNMR

219580-11-7(PD 173074)Related Search:

2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE PD 123319 ditrifluoroacetate Pictilisib JNJ-10198409
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n-[2-[[4-(diethylamino)butyl]amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-n'-(1,1-dimethylethyl)urea N-[2-[[4-(diethylaMino)butyl]aMino]-6-(3,5-diMethoxyphenyl)pyrido[2,3-d ]pyriMidin-7-yl]-N'-(1,1-diMethylethyl)- PD173074/PD-173074 1-(tert-butyl)-3-(2-((4-(diethylaMino)butyl)aMino)-6-(3,5-diMethoxyphenyl)pyrido[2,3-d]pyriMidin-7-yl)urea 1-(tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin- Urea, N-[2-[[4-(diethylaMino)butyl]aMino]-6-(3,5-diMethoxyphenyl)pyrido[2,3-d]pyriMidin-7-yl]-N'-(1,1-diMethylethyl)- PD176074 N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea PD 173074 PD 173074 N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea PD-0173074 1-(tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimid FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 PD 173074, Free Base PD173074, >=98% CS-458 FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 - CAS 219580-11-7 - Calbiochem FGF/VEGF Receptor Tyrosine Kinase Inhibitor PD 173074;PD-173074;FGF/VEGF RECEPTOR TYROSINE KINASE INHIBITOR 1-(tert-Butyl)-3-[7-[[4-(diethylamino)butyl]amino]-3-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-2-yl]urea Cholest-5-en-3-ol,(9α)- PD-173074 FGFR1 FGFR3 inhibitor ab141117 Inhibitor,Fibroblast growth factor receptor,PD173074,Apoptosis,Vascular endothelial growth factor receptor,inhibit,PD 173074,FGFR,PD-173074,VEGFR N-[2-[[4-(diethylamino)butyl]amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea 219580-11-7 C28H41N7O3 Antineoplastic API Aromatics Bases & Related Reagents Heterocycles Inhibitors Intermediates & Fine Chemicals Nucleotides Pharmaceuticals