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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Transmembrane Transporters >CRM1 inhibitors >KPT-330

KPT-330

KPT-330 Structure
CAS No.
1393477-72-9
Chemical Name:
KPT-330
Synonyms
Selinexor;Xpovio;KPT-330;CS-1056;Aloradine;Selinexorb;KPT330; KPT 330;KPT330,Selinexor;KPT-330 USP/EP/BP;Selinexor (KPT-330)
CBNumber:
CB12681123
Molecular Formula:
C17H11F6N7O
Molecular Weight:
443.31
MOL File:
1393477-72-9.mol
Modify Date:
2025/1/9 17:41:46
Request For Quotation

KPT-330 Properties

Density 1.55±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO (up to at least 25 mg/ml). or in Ethanol (up to at least 25 mg/ml)
pka 9.74±0.43(Predicted)
form solid
color Off-white
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H332-H302-H312
Precautionary statements  P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501

KPT-330 Chemical Properties,Uses,Production

Uses

KPT 330 is a chromosome maintenance protein 1 (CRM1) inhibitor. KPT 330 suppresses downstream effectors of B-cell activation, proliferation and migration in chronic lymphocytic leukemia cells.

KPT-330 Preparation Products And Raw materials

Raw materials

3,5-Bis(trifluoromethyl)benzonitrile 2-Hydrazinopyrazine 3,5-DI(TRIFLUOROMETHYL)BENZENE-1-CARBOTHIOAMIDE (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid 3,5-Di(trifluoromethyl)benzamide
(Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate
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Preparation Products

3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazole

KPT-330 Suppliers

Global( 164)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Venkatasai Life Sciences +91-9908134868 +91-8008303069 Hyderabad, India 186 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6514 58 Inquiry
Hangzhou ICH Biofarm Co., Ltd +86-0571-28186870; +undefined8613073685410 China 1010 58 Inquiry
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. +86-18600796368 +86-18600796368 China 484 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32956 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29880 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39894 58 Inquiry
Supplier Advantage
Venkatasai Life Sciences 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
SynZeal Research Pvt Ltd 58
Hangzhou ICH Biofarm Co., Ltd 58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58

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KPT-330 Spectrum

KPT-330(1393477-72-9)MSKPT-330(1393477-72-9)1HNMR

1393477-72-9(KPT-330)Related Search:

PD 173074 KPT-330, (E)-RN Verdinexor (KPT-335) Bortezomib (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3,3-
MK-2206 2HCl OTX015 KPT-185 Ruxolitinib CONCANAMYCIN A
Prostaglandin E2 SGC-GAK-1 2-BROMOHEXADECANOIC ACID 3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazole (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid
2-Propenoic acid, 3-iodo-, 1-methylethyl ester, (2Z)- (Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate
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KPT-330 (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide Selinexor (KPT-330) (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)- Aloradine KPT330,Selinexor (KPT330)(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide SELINEXOR;KPT330;KPT 330 KPT-330,Selinexor, >98% KPT330; KPT 330 CS-1056 (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide(Selinexor) Selinexor free base KPT-330 USP/EP/BP Selinexor Selinexor (KPT 330),Selinexor (KPT330) Xpovio (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide Selinexorb Avatrombopag Impurity 32 Hydrochloride 1393477-72-9 C17H11F6N7O Inhibitors API