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Verdinexor (KPT-335)

CAS No.: 1392136-43-4

Chemical Name:: Verdinexor (KPT-335)

Synonyms: CS-1798;KPT-335;Verdinexor;KPT335(Verdinexor);Verdinexor(KPT-335);Verdinexor (KPT-335) USP/EP/BP;Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin-;(Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyridin-2-ylprop-2-enehydrazide;(Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin-2-yl)acrylohydrazide;(Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin-2-yl)acrylohydrazide

CBNumber:: CB02680705

Molecular Formula:: C18H12F6N6O

Molecular Weight:: 442.32

MOL File:: 1392136-43-4.mol

Modify Date:: 2024/7/2 8:54:57

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Verdinexor (KPT-335) Properties

Density	1.49±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	≥44.2 mg/mL in DMSO; insoluble in H2O; ≥2.31 mg/mL in EtOH with ultrasonic
form	solid
pka	10.04±0.43(Predicted)
color	Light yellow to yellow
CAS DataBase Reference	1392136-43-4

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

Verdinexor (KPT-335) Chemical Properties,Uses,Production

Uses

Verdinexor is a potent and selective SINE inhibitor, shown to be effective in treating influenza A virus infection in mice and ferret models.

Verdinexor (KPT-335) Preparation Products And Raw materials

Raw materials

3,5-Bis(trifluoromethyl)benzonitrile 3,5-DI(TRIFLUOROMETHYL)BENZENE-1-CARBOTHIOAMIDE (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid 3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazole (Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate

2-Hydrazinopyridine

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Preparation Products

Verdinexor (KPT-335) Suppliers

Global( 68)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32836	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29888	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24099	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +8615988602810	China	3000	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	China	20293	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Zhengzhou Anbu Chem Co.,Ltd	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Aladdin Scientific	58

Verdinexor (KPT-335) Spectrum

Verdinexor (KPT-335)(1392136-43-4)¹HNMR

1392136-43-4(Verdinexor (KPT-335))Related Search:

3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazole (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylic acid 2-Propenoic acid, 3-iodo-, 1-methylethyl ester, (2Z)- (Z)-isopropyl 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate PD 173074

KPT-330, (E)-RN (Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-1-(3,3- KPT-330 Selumetinib Dasatinib

Gemcitabine Phloretin β-Estradiol Lapatinib Ditosylate

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Z)-3-(3-(3,5-bis(trifluoroMethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin- KPT-335 Verdinexor Verdinexor(KPT-335) (2Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]- 2-propenoic acid-2-(2-pyridinyl)hydrazide (2Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N -(pyridin-2-yl)prop-2-enehydrazide Verdinexor(KPT-335) (KPT335)(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin-2-yl)acrylohydrazide CS-1798 (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyridin-2-ylprop-2-enehydrazide KPT335(Verdinexor) 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyridinyl)hydrazide, (2Z)- Verdinexor (KPT-335) USP/EP/BP (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin-2-yl)acrylohydrazide (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyridin-2-yl)acrylohydrazide 1392136-43-4 C18H12F6N6O Inhibitors API