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Lapatinib Ditosylate

Lapatinib Ditosylate Structure
CAS No.
388082-77-7
Chemical Name:
Lapatinib Ditosylate
Synonyms
GW-572016F;Tykerb Ditosylat;apatinib DitosyL;Tykerb Ditosylate;Tykerb(lapatinib);Lapatinib Tosylate;Lapatinib ditosylate;GW-572016 ditosylate;GW 572016 ditosylate;Lapatinib ditasylate
CBNumber:
CB11176387
Molecular Formula:
C36H34ClFN4O7S2
Molecular Weight:
753.26
MOL File:
388082-77-7.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:59
Request For Quotation

Lapatinib Ditosylate Properties

Melting point 240-2420C
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility ≥24.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form solid
color Light yellow to yellow
Water Solubility Water: Insoluble
CAS DataBase Reference 388082-77-7

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS02
Signal word  Danger
Hazard statements  H315-H319-H225
Precautionary statements  P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235
Safety Statements  24/25
HS Code  29420000

Lapatinib Ditosylate Chemical Properties,Uses,Production

Description

Lapatinib, an ErB-1 and ErB-2 dual kinase inhibitor, was launched for the treatment of advanced or metastatic HER2 (ErbB2) positive breast cancer in women who have received prior therapy. The drug was discovered and developed by GlaxoSmithKline and is also currently being evaluated for several additional cancer indications.

Chemical Properties

Yellow Solid

Uses

Lapatinib Ditosylate (GW572016, GW2016, Tykerb, Tyverb) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

Lapatinib Ditosylate Preparation Products And Raw materials

Raw materials

Preparation Products

Lapatinib Ditosylate Suppliers

Global( 226)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Dodhia Group +91-9619867345 +91-9619867345 Mumbai, India 129 58 Inquiry
Vannsh Life Sciences Pvt Ltd +91-4023555246 +91-9642555246 Hyderabad, India 15 58 Inquiry
Salvavidas Pharmaceutical Pvt., Ltd. +91-2612538898 +91-9327127459 Gujarat, India 34 58 Inquiry
Basil Drugs AND Pharmaceuticals Pvt Ltd +91-2249700250 +91-9619320820 Mumbai, India 108 58 Inquiry
Kekule Pharma Limited +919849798889 Hyderabad, India 59 58 Inquiry
Raising Sun Pharma +91-9399941155 +91-9399941155 Telangana, India 127 58 Inquiry
Sumar Biotech LLP +91-7984183709 +91-9824575381 Gujarat, India 22 58 Inquiry
Beta Drugs +91-9316590666 +91-7015991921 Haryana, India 34 58 Inquiry
Aspen Biopharma Labs Pvt Ltd +91-9248058660 +91-9248058662 Telangana, India 234 58 Inquiry
Kekule Life Sciences Limited +91-9963474090 +91-9963474090 AndhraPradesh, India 19 58 Inquiry
Supplier Advantage
Dodhia Group 58
Vannsh Life Sciences Pvt Ltd 58
Salvavidas Pharmaceutical Pvt., Ltd. 58
Basil Drugs AND Pharmaceuticals Pvt Ltd 58
Kekule Pharma Limited 58
Raising Sun Pharma 58
Sumar Biotech LLP 58
Beta Drugs 58
Aspen Biopharma Labs Pvt Ltd 58
Kekule Life Sciences Limited 58

Lapatinib Ditosylate Spectrum

Lapatinib Ditosylate(388082-77-7)1HNMR

388082-77-7(Lapatinib Ditosylate)Related Search:

Lapatinib impurity L Lapatinib 2-Fluoro Impurity Lapatinib 4-Fluoro Impurity N-De[2-(Methylsulfonyl)ethyl] Lapatinib Lapatinib iMpurity
Lapatinib Impurity 16 Lapatinib IMpurity 10 Lapatinib Sorafenib tosylate Gefitinib
Erlotinib hydrochloride Crizotinib Ruxolitinib Olaparib 3-Chloro-4-(3-fluorobenzyloxy)aniline
Lapatinib Lapatinib Ditosylate 2-AMINOETHANETHIOL P-TOLUENESULFONATE
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Lapatinib ditosylate 4-QuinazolinaMine, N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-6-[5-[[[2-(Methylsulfonyl)ethyl]aMino]Methyl]-2-furanyl]-, 4-Methylbenzenesulfonate (1:2) Lapatinib Ditosylate (Tykerb) GW 572016 ditosylate GW-572016 ditosylate GW-572016F Tykerb Ditosylat GW-572016F Ditosylate N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis(4-methylbenzenesulfonate) Ditosylate Tykerb Ditosylate N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(Methylsulfonyl)ethyl]aMino}Methyl)-2-furyl]-4-quinazolinaMine 4-Methylbenzenesulfonate (1:2) Lapatinib ditasylate N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(Methylsulfonyl)ethyl)aMino)Methyl)furan-2-yl)quinazolin-4-aMine bis(4-Methylbenzenesulfonate) Lapatinib (GW-572016) Ditosylate N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine,di4-methylbenzenesulfonate Tykerb(lapatinib) N-{3-chloro-4-[(3-fluorobenzyl)oxyl]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine bis(4-methylBenzenesulfonate) TYKERB DITOSYLATE; GW 572016 DITOSYLATE; GW-572016 DITOSYLATE GW 572016 DITOSYLATE;GW-572016 DITOSYLATE apatinib DitosyL Lapatinib Tosylate Lapatinib Ditosylate USP/EP/BP Lapatinib ditosylate anhydrous Lapatinib Ditosylate (GW-572016, Tykerb) dipyrido[3,2-a:2',7'-c]phenazine N-3-Chloro-4-(3-fluorophenyl)methoxyphenyl-6-5-2-(methylsulfonyl)ethylaminomethyl-furan-2-yl-4-amino-quinazoline tosylate (1:2) 388082-77-7 C43H42ClFN4O10S3 Inhibitors Final material Intermediates & Fine Chemicals Pharmaceuticals Tyrosine Kinase Inhibitors