Y27632 (hydrochloride)
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- ₹14800 - ₹90886.7
- Product name: Y27632 (hydrochloride)
- CAS: 129830-38-2
- MF: C14H23Cl2N3O
- MW: 320.25792
- EINECS:813-428-5
- MDL Number:MFCD03490488
- Synonyms:(R)-4-(1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride;Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR;Y-27632 dihydrochloride, >=98%;trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride Y 27632 dihydrochloride;Y 27632 dihydrochloride (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride;Y27632 (hydrochloride);(+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride;trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
3 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberY0018
- Product descriptionY 27632 Dihydrochloride
- Packaging50MG
- Price₹14800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberY0503
- Product descriptionY-27632 dihydrochloride ≥98% (HPLC)
- Packaging1MG
- Price₹21541.75
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberY0503
- Product descriptionY-27632 dihydrochloride ≥98% (HPLC)
- Packaging5MG
- Price₹90886.7
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | Y0018 | Y 27632 Dihydrochloride | 50MG | ₹14800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | Y0503 | Y-27632 dihydrochloride ≥98% (HPLC) | 1MG | ₹21541.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | Y0503 | Y-27632 dihydrochloride ≥98% (HPLC) | 5MG | ₹90886.7 | 2022-06-14 | Buy |
Properties
Melting point :258℃
storage temp. :2-8°C
solubility :H2O: soluble14mg/mL
form :powder
color :white to beige
optical activity :[α]/D +3.0 to +5.0°, c =1.0 in methanol
biological source :synthetic (organic)
Water Solubility :H2O: 14mg/mL
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.
storage temp. :2-8°C
solubility :H2O: soluble14mg/mL
form :powder
color :white to beige
optical activity :[α]/D +3.0 to +5.0°, c =1.0 in methanol
biological source :synthetic (organic)
Water Solubility :H2O: 14mg/mL
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Warning | |||||||
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Description
Y-27632 dihydrochloride is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 dihydrochloride increases the release of neurotransmitters from cholinergic nerves. Studies conducted on smooth muscle preparations suggest that Y-27632 dihydrochloride suppresses nerve-mediated contractile responses stimulated by acetylcholine and noradrenaline. Furthermore, studies on lung tissue damage in rats suggest that Y-27632 dihydrochloride can restore the damage caused by oleic acid by inhibition of ROCK-1 and ROCK-2. Y-27632 dihydrochloride also inhibits protein kinase C related kinase, PRK2.More related product prices
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