YC-1
- ₹20080.38 - ₹71878
- Product name: YC-1
- CAS: 170632-47-0
- MF: C19H16N2O2
- MW: 304.34
- EINECS:
- MDL Number:MFCD06407798
- Synonyms:2-Furanmethanol, 5-[1-(phenylmethyl)-1H-indazol-3-yl]-;Nsc728165;(5-(1-Benzyl-1H-indazol-3-yl)furan-2-yl)Methanol;YC 1 (pharMaceutical);1-Benzyl-3-(5-hydroxymethylfur-2-yl)indazole;1-benzyl-3-(5-hydroxymethyl-furan-2-yl)indazole;Lificiguat(YC-1);5-[1-(PHENYLMETHYL)-1H-INDAZOL-3-YL]-2-FURANMETHANOL
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberY102
- Product descriptionYC-1 powder
- Packaging5MG
- Price₹20080.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number688100
- Product descriptionYC-1 - CAS 170632-47-0 - Calbiochem A nitric oxide-independent, superoxide-sensitive activator of soluble guanylyl cyclase.
- Packaging5MG
- Price₹23550
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberY102
- Product descriptionYC-1 powder
- Packaging25MG
- Price₹71878
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | Y102 | YC-1 powder | 5MG | ₹20080.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 688100 | YC-1 - CAS 170632-47-0 - Calbiochem A nitric oxide-independent, superoxide-sensitive activator of soluble guanylyl cyclase. | 5MG | ₹23550 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | Y102 | YC-1 powder | 25MG | ₹71878 | 2022-06-14 | Buy |
Properties
Melting point :110-112℃
Boiling point :522.2±50.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: 12 mg/mL
pka :13.83±0.10(Predicted)
form :solid
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :522.2±50.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: 12 mg/mL
pka :13.83±0.10(Predicted)
form :solid
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
YC-1 is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase. It inhibits collagen (10 μg/ml) and thrombin (0.1 U/ml) induced platelet aggregation with IC50 values of 11.7-14.6 and 57.3-59.3 μM, respectively. In the absence of NO or carbon monoxide (CO), 200 μM YC-1 increases the activity of purified soluble guanylyl cyclase 12-fold, with an ED50 value of 20 μM. At a concentration of 200 μM, YC-1 potentiates the maximal activity of soluble guanylyl cyclase in the presence of NO or CO by 40% and >3,000%, respectively.More related product prices
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