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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cell Cycle >ROCK inhibitors >Y27632 (hydrochloride)

Y27632 (hydrochloride)

Y27632 (hydrochloride) Structure
  • ₹14800 - ₹90886.7
  • Product name: Y27632 (hydrochloride)
  • CAS: 129830-38-2
  • MF: C14H23Cl2N3O
  • MW: 320.25792
  • EINECS:813-428-5
  • MDL Number:MFCD03490488
  • Synonyms:(R)-4-(1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride;Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR;Y-27632 dihydrochloride, >=98%;trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride Y 27632 dihydrochloride;Y 27632 dihydrochloride (+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride;Y27632 (hydrochloride);(+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride;trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberY0018
  • Product descriptionY 27632 Dihydrochloride
  • Packaging50MG
  • Price₹14800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberY0503
  • Product descriptionY-27632 dihydrochloride ≥98% (HPLC)
  • Packaging1MG
  • Price₹21541.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberY0503
  • Product descriptionY-27632 dihydrochloride ≥98% (HPLC)
  • Packaging5MG
  • Price₹90886.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) Y0018 Y 27632 Dihydrochloride 50MG ₹14800 2022-05-26 Buy
Sigma-Aldrich(India) Y0503 Y-27632 dihydrochloride ≥98% (HPLC) 1MG ₹21541.75 2022-06-14 Buy
Sigma-Aldrich(India) Y0503 Y-27632 dihydrochloride ≥98% (HPLC) 5MG ₹90886.7 2022-06-14 Buy

Properties

Melting point :258℃
storage temp. :2-8°C
solubility :H2O: soluble14mg/mL
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Y-27632 dihydrochloride is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 dihydrochloride increases the release of neurotransmitters from cholinergic nerves. Studies conducted on smooth muscle preparations suggest that Y-27632 dihydrochloride suppresses nerve-mediated contractile responses stimulated by acetylcholine and noradrenaline. Furthermore, studies on lung tissue damage in rats suggest that Y-27632 dihydrochloride can restore the damage caused by oleic acid by inhibition of ROCK-1 and ROCK-2. Y-27632 dihydrochloride also inhibits protein kinase C related kinase, PRK2.

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