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3-(4-Pyridyl)indole

3-(4-Pyridyl)indole Structure
  • ₹13100
  • Product name: 3-(4-Pyridyl)indole
  • CAS: 7272-84-6
  • MF: C13H10N2
  • MW: 194.23
  • EINECS:
  • MDL Number:
  • Synonyms:3-(4-Pyridinyl)-;Rho Kinase Inhibitor III, Rockout;1H-Indole, 3-(4-pyridinyl)-;3-(4-Pyridinyl)-1H-indole;3-(4-Pyridyl)indole;Rho Kinase Inhibitor III, Rockout - CAS 7272-84-6 - Calbiochem;Rho Kinase Inhibitor III;RHO KINASE INHIBITOR III; ROCK INHIBITOR III; ROCKOUT
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product number555553
  • Product descriptionRho Kinase Inhibitor III, Rockout - CAS 7272-84-6 - Calbiochem The Rho Kinase Inhibitor III, Rockout, also referenced under CAS 7272-84-6, controls the biological activity of Rho Kinase. This small molecule/inhibi
  • Packaging10MG
  • Price₹13100
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 555553 Rho Kinase Inhibitor III, Rockout - CAS 7272-84-6 - Calbiochem The Rho Kinase Inhibitor III, Rockout, also referenced under CAS 7272-84-6, controls the biological activity of Rho Kinase. This small molecule/inhibi 10MG ₹13100 2022-06-14 Buy

Properties

storage temp. :+2C to +8C
solubility :DMSO, Methanol
form :Yellow solid
color :Yellow
Stability :Light Sensitive
CAS DataBase Reference :7272-84-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 μM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay. It also inhibits ROCK-II and PRK2, another Rho-dependent kinase, with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency.

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Suppliers and manufacturers

Career Henan Chemica Co
3-(4-Pyridyl)indole
₹0.37 /1g
3-(4-Pyridyl)indole CAS:7272-84-6
CLEARSYNTH LABS LTD.
Aladdin Scientific RD International Technology Co., Limited Biokitchen ChemeGen(Shanghai) Biotechnology Co.,Ltd. MedBioPharmaceutical Technology Inc Cayman Chemical Company Shanghai EFE Biological Technology Co., Ltd. DC Chemicals