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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Fasudil hydrochloride

Fasudil hydrochloride

Fasudil hydrochloride Structure
  • ₹7800
  • Product name: Fasudil hydrochloride
  • CAS: 105628-07-7
  • MF: C14H18ClN3O2S
  • MW: 327.83
  • EINECS:805-833-0
  • MDL Number:MFCD00943198
  • Synonyms:1-(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE HYDROCHLORIDE;Fasudil Monohydrochloride;(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, 2HCL;5-(1,4-DIAZEPAN-1-YLSULFONYL)ISOQUINOLINE HYDROCHLORIDE;HEXAHYDRO-1-(5-ISOQUINOLINYLSULFONYL)-MONOHYDROCHLORIDE;HA-1077;HA-1077 DIHYDROCHLORIDE;FASUDEL
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Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberF0839
  • Product descriptionFasudil Hydrochloride
  • Packaging100MG
  • Price₹7800
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F0839 Fasudil Hydrochloride 100MG ₹7800 2022-05-26 Buy

Properties

Melting point :220.5°; mp 219.3° (Shirotani)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >200 mg/mL
form :solid
color :white
Water Solubility :Soluble in water and dimethyl sulfoxide. Insoluble in ethanol.
Merck :14,3942
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChI :InChI=1S/C14H17N3O2S.2ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;;/h1,3-5,7,11,15H,2,6,8-10H2;2*1H
InChIKey :LFVPBERIVUNMGV-UHFFFAOYSA-N
SMILES :N1(S(C2=CC=CC3=C2C=CN=C3)(=O)=O)CCCNCC1.[H]Cl.[H]Cl
CAS DataBase Reference :105628-07-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Fasudil monohydrochloride is used in the prevention and treating cardiovascular and cerebrovascular diseases. It is also used in the inhibition of proliferation of vascular smooth muscle cells. It serves as a selective Rho-associated protein kinase (ROCK) inhibitor. Further, it protects against methyl mercury-induced axonal degeneration.

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