FASUDIL
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- ₹14260
- Product name: FASUDIL
- CAS: 103745-39-7
- MF: C14H17N3O2S
- MW: 291.37
- EINECS:816-154-4
- MDL Number:MFCD00153805
- Synonyms:Fasudil Hydrochloride Injection;1-(5-ISOQUINOLINE-SULFONYL)-HOMOPIPERAZINE;at877 ;hexahydro-1-(5-isoquinolinylsulfonyl)-1h-4-diazepine ;HA-1077 DIHYDROCHLORIDE NOVEL VASODILATO R AGE;HA 1077, DIHYDROCHLORIDE, 99+%;FASUDIL;Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product number371970
- Product descriptionHA 1077, Dihydrochloride - CAS 103745-39-7 - Calbiochem A cell-permeable, reversible, and ATP-competitive Ca2+ antagonist with anti-vasospastic properties.
- Packaging1MG
- Price₹14260
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 371970 | HA 1077, Dihydrochloride - CAS 103745-39-7 - Calbiochem A cell-permeable, reversible, and ATP-competitive Ca2+ antagonist with anti-vasospastic properties. | 1MG | ₹14260 | 2022-06-14 | Buy |
Properties
Boiling point :506.2±60.0 °C(Predicted)
Density :1.289±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :H2O: >200 mg/mL
form :solid
pka :9.73±0.20(Predicted)
color :white
Water Solubility :Soluble in water or DMSO
CAS DataBase Reference :103745-39-7(CAS DataBase Reference)
Density :1.289±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :H2O: >200 mg/mL
form :solid
pka :9.73±0.20(Predicted)
color :white
Water Solubility :Soluble in water or DMSO
CAS DataBase Reference :103745-39-7(CAS DataBase Reference)
Safety Information
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Description
HA-1077 dihydrochloride has been shown to be a vasodilating agent as well as a potent inhibitor of Rock-2 (Rho-associated Kinase II), cGKI (cGMP-dependent protein kinase), PKA (cAMP-dependent protein kinase), MYLK, and CaMKII. Rho kinase signaling pathways are thought to cause invasion, migration, and proliferation of certain cells. Studies have shown this compound can also inhibit myosin light chain kinase in vitro and suppress cell rounding by myosin light chain phosphorylation. Mechanistic experiments report that HA-1077 inhibits vascular smooth muscle contraction by acting as a calcium channel protein inhibitor. HA-1077 dihydrochloride is an inhibitor of MSK1, PKC, PRK2 and Rsk-2.More related product prices
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Suppliers and manufacturers
CLEARSYNTH LABS LTD.
Pharmaffiliates Analytics and Synthetics P. Ltd
Pharma Affiliates
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
