Temsirolimus
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- ₹14115.8 - ₹51732.68
- Product name: Temsirolimus
- CAS: 162635-04-3
- MF: C56H87NO16
- MW: 1030.29
- EINECS:686-177-0
- MDL Number:MFCD00934421
- Synonyms:42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropa;Temsirolimus(CCI-779);TEMSIROLIMUS;CCL-779;Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate;TeMsiroliMus (CCI-779, Torisel);rapaMycin 42-ester with 3-hydroxy-2-(hydroxyMethyl)-2-Methylpropionic acid;42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin
3 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberT3574
- Product descriptionTemsirolimus
- Packaging50MG
- Price₹17600
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0020
- Product descriptionTemsirolimus ≥98% (HPLC)
- Packaging25MG
- Price₹51732.68
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0020
- Product descriptionTemsirolimus ≥98% (HPLC)
- Packaging5MG
- Price₹14115.8
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | T3574 | Temsirolimus | 50MG | ₹17600 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | PZ0020 | Temsirolimus ≥98% (HPLC) | 25MG | ₹51732.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PZ0020 | Temsirolimus ≥98% (HPLC) | 5MG | ₹14115.8 | 2022-06-14 | Buy |
Properties
Melting point :99-101°C
Boiling point :1048.4±75.0 °C(Predicted)
Density :1.21
Flash point :587.8℃
storage temp. :room temp
solubility :Soluble in chloroform, methanol.
pka :10.40±0.70(Predicted)
form :powder
color :white to off-white
Merck :14,9142
InChIKey :CBPNZQVSJQDFBE-FUXHJELOSA-N
Boiling point :1048.4±75.0 °C(Predicted)
Density :1.21
Flash point :587.8℃
storage temp. :room temp
solubility :Soluble in chloroform, methanol.
pka :10.40±0.70(Predicted)
form :powder
color :white to off-white
Merck :14,9142
InChIKey :CBPNZQVSJQDFBE-FUXHJELOSA-N
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Rapamycin is an immunosuppressant that specifically interacts with the cytosolic FK-binding protein 12 to form a complex which inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding to mTOR Complex 1. Temsirolimus is a dihydroxymethyl propionic acid ester of rapamycin with improved solubility that specifically inhibits mTOR signaling with a potency similar to that of rapamycin. Treatment with temsirolimus leads to cell cycle arrest in the G1 phase and also inhibition of tumor angiogenesis by reducing synthesis of VEGF. Temsirolimus demonstrates cytostatic activity in several xenograft models of human tumors in nude mice, including glioblastomas, prostate carcinoma, pancreatic, liver, and breast cancers, and medulloblastoma.Related product price
- 3-(4-Hydroxyphenyl)propionic acid
₹1667.05-20773 - Rapamycin
₹4194-370089 - CHLOROPHOSPHONAZO III
₹4180-73610