Rapamycin
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- ₹4194 - ₹370089
- Product name: Rapamycin
- CAS: 53123-88-9
- MF: C51H79NO13
- MW: 914.17
- EINECS:610-965-5
- MDL Number:MFCD00867594
- Synonyms:AY 22989;23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE;NSC-226080;RAPAMYCIN;RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS;RPM;antibioticay22989 ;(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
15 prices
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Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
- ottokemi
Package
- 1MG
- 5MG
- 10MG
- 100μG
- 25MG
- 100mg
- 1gm
- 1ML
- 5gm
- 200μL
- ManufacturerSigma-Aldrich(India)
- Product number553210
- Product descriptionRapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM)
- Packaging100μG
- Price₹6490
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS-015
- Product descriptionSirolimus solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹23487.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR8781
- Product descriptionRapamycin Ready Made Solution, 2.5?mg/mL in DMSO (2.74 mM), from Streptomyces hygroscopicus
- Packaging200μL
- Price₹30935.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number553210
- Product descriptionRapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM)
- Packaging1MG
- Price₹31000
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR0395
- Product descriptionRapamycin from Streptomyces hygroscopicus ≥95% (HPLC), powder
- Packaging1MG
- Price₹36393.65
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number37094
- Product descriptionRapamycin VETRANAL?, analytical standard
- Packaging10MG
- Price₹42618.03
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number553210
- Product descriptionRapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM)
- Packaging5MG
- Price₹53810.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number553210
- Product descriptionRapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM)
- Packaging10MG
- Price₹66980.01
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberR0097
- Product descriptionRapamycin
- Packaging25MG
- Price₹4200
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number R 1206
- Product descriptionRapamycin, ≥98% (HPLC)
- Packaging25mg
- Price₹4194
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number R 1206
- Product descriptionRapamycin, ≥98% (HPLC)
- Packaging100mg
- Price₹13059
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number R 1210
- Product descriptionRapamycin, from streptomyces hygroscopicus 95%
- Packaging1mg
- Price₹33039
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number R 1206
- Product descriptionRapamycin, ≥98% (HPLC)
- Packaging1gm
- Price₹86049
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number R 1210
- Product descriptionRapamycin, from streptomyces hygroscopicus 95%
- Packaging5mg
- Price₹130059
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number R 1206
- Product descriptionRapamycin, ≥98% (HPLC)
- Packaging5gm
- Price₹370089
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 553210 | Rapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM) | 100μG | ₹6490 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S-015 | Sirolimus solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹23487.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | R8781 | Rapamycin Ready Made Solution, 2.5?mg/mL in DMSO (2.74 mM), from Streptomyces hygroscopicus | 200μL | ₹30935.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 553210 | Rapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM) | 1MG | ₹31000 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | R0395 | Rapamycin from Streptomyces hygroscopicus ≥95% (HPLC), powder | 1MG | ₹36393.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 37094 | Rapamycin VETRANAL?, analytical standard | 10MG | ₹42618.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 553210 | Rapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM) | 5MG | ₹53810.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 553210 | Rapamycin - CAS 53123-88-9 - Calbiochem Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC?? = 50 pM) | 10MG | ₹66980.01 | 2022-06-14 | Buy |
| TCI Chemicals (India) | R0097 | Rapamycin | 25MG | ₹4200 | 2022-05-26 | Buy |
| ottokemi | R 1206 | Rapamycin, ≥98% (HPLC) | 25mg | ₹4194 | 2022-05-26 | Buy |
| ottokemi | R 1206 | Rapamycin, ≥98% (HPLC) | 100mg | ₹13059 | 2022-05-26 | Buy |
| ottokemi | R 1210 | Rapamycin, from streptomyces hygroscopicus 95% | 1mg | ₹33039 | 2022-05-26 | Buy |
| ottokemi | R 1206 | Rapamycin, ≥98% (HPLC) | 1gm | ₹86049 | 2022-05-26 | Buy |
| ottokemi | R 1210 | Rapamycin, from streptomyces hygroscopicus 95% | 5mg | ₹130059 | 2022-05-26 | Buy |
| ottokemi | R 1206 | Rapamycin, ≥98% (HPLC) | 5gm | ₹370089 | 2022-05-26 | Buy |
Properties
Melting point :183-185°C
alpha :D25 -58.2° (methanol)
Boiling point :799.83°C (rough estimate)
Density :1.0352 (rough estimate)
vapor pressure :0.56 hPa ( 20 °C)
refractive index :1.5280 (estimate)
Flash point :87 °C
storage temp. :-20°C
solubility :ethanol: soluble2MM
pka :10.40±0.70(Predicted)
form :solution
color :colorless to yellow
Water Solubility :Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.
Sensitive :Moisture Sensitive/Light Sensitive/Hygroscopic
Merck :14,8114
Stability :Stable for 2 years? from date of purchase as supplied.? Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
CAS DataBase Reference :53123-88-9(CAS DataBase Reference)
alpha :D25 -58.2° (methanol)
Boiling point :799.83°C (rough estimate)
Density :1.0352 (rough estimate)
vapor pressure :0.56 hPa ( 20 °C)
refractive index :1.5280 (estimate)
Flash point :87 °C
storage temp. :-20°C
solubility :ethanol: soluble2MM
pka :10.40±0.70(Predicted)
form :solution
color :colorless to yellow
Water Solubility :Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.
Sensitive :Moisture Sensitive/Light Sensitive/Hygroscopic
Merck :14,8114
Stability :Stable for 2 years? from date of purchase as supplied.? Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
CAS DataBase Reference :53123-88-9(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Rapamycin is an immunosuppressant that is used primarily to prevent the rejection of organ and bone marrow transplant. It was first described as a potent inhibitor of IL-2 activation of lymphocytes (IC50 = 5 pM). It is now known that rapamycin specifically interacts with the cytosolic FK-binding protein 12 (FKBP12) to form a complex which inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding to mTOR Complex 1 (mTORC1). Rapamycin and other inhibitors of mTORC1 signaling show potential in treating cancer, adipogenesis, diabetes, tuberous sclerosis, and cardiovascular disease.Related product price
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