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ChemicalBook > Product Catalogue >API >Antibiotics >Macrolides >Azithromycin

Azithromycin

Azithromycin Structure
  • ₹19355.1
  • Product name: Azithromycin
  • CAS: 83905-01-5
  • MF: C38H72N2O12
  • MW: 748.98
  • EINECS:617-500-5
  • MDL Number:MFCD00873574
  • Synonyms:10% aqueous azithromycin;70% water-soluble azithromycin;N-METHYL-11-AZA-10-DEOXO-10-DIHYDROERYTHROMYCIN A;11-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-2-ethyl-3,4,10-tr;11-(4-DIMETHYLAMINO-3-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY)-2-ETHYL-3,4,10-TRIHYDROXY-14-(5-HYDROXY-4-METHOXY-4,6-DIMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-3,5,6,8,10,12,13-HEPTAMETHYL-1-OXA-6-AZA-CYCLOPENTADECAN-15-ONE;9-DEOXO-9ALPHA-METHYL-9ALPHA-AZA-HOMOERYTHROMYCIN A;9-deoxo-9a-methyl-9a-aza-homoerythromycin a;AZITHROMYCIN
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Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product number75199
  • Product descriptionAzithromycin
  • Packaging25MG
  • Price₹19355.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 75199 Azithromycin 25MG ₹19355.1 2022-06-14 Buy

Properties

Melting point :113-115°C
Boiling point :822.1±65.0 °C(Predicted)
alpha :D20 -37° (c = 1 in CHCl3)
Density :1.18±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Practically insoluble in water, freely soluble in anhydrous ethanol and in methylene chloride.
pka :pKa 8.74 (H2O t=25 I=0.167) (Uncertain);9.45(H2O t=25 I=0.167) (Uncertain)
form :Solid
color :White to Off-White
optical activity :[α]/D 45±2°, c = 1% in ethanol
BCS Class :4
Stability :Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference :83905-01-5(CAS DataBase Reference)
EPA Substance Registry System :Azithromycin (83905-01-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Azithromycin is a macrolide antibiotic with high stability at acidic pH, long half-life, and favorable effectiveness against a range of organisms. In addition, it interferes poorly with the cytochrome P450 system in vitro, limiting side effects related to drug interactions. Azithromycin is effective, in combination with chloroquine, for protection against malaria.

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