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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >EveroliMus-d4

EveroliMus-d4

EveroliMus-d4 Structure
  • ₹56051.85
  • Product name: EveroliMus-d4
  • CAS: 1338452-54-2
  • MF: C53H79D4NO14
  • MW: 962.249067112
  • EINECS:
  • MDL Number:
  • Synonyms:EveroliMus-d4 (~90%);Everolimus-d4;Everolimus D4Q: What is Everolimus D4 Q: What is the CAS Number of Everolimus D4 Q: What is the storage condition of Everolimus D4 Q: What are the applications of Everolimus D4;EVEROLIMUS (2-HYDROXYETHYL-D4, 98%);Everolimus Impurity 24(Everolimus-d4);Everolimus-d4 (Everolimus Impurity)
1 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1ML
  • ManufacturerSigma-Aldrich(India)
  • Product numberE-070
  • Product descriptionEverolimus-D4 solution 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹56051.85
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) E-070 Everolimus-D4 solution 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹56051.85 2022-06-14 Buy

Properties

storage temp. :Store at 4°C
solubility :Chloroform: Soluble,Methanol: Soluble
form :A solid
color :White to off-white
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Everolimus-d4 is intended for use as an internal standard for the quantification of everolimus by GC- or LC-MS. Everolimus is a hydroxyethyl ether form of rapamycin that inhibits mTOR signaling through both mTORC1 and mTORC2 when added to cells at 20 nM. It is orally available and shows improved pharmacokinetics and pharmacodynamics over rapamycin. Through its inhibition of mTOR, everolimus inhibits cell proliferation, metabolism, and angiogenesis in certain types of cancer. It also acts as an immunosuppressive agent in the context of organ transplantation.

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