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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Neuronal Signaling >AMPA and kainate receptors >Memantine HCl

Memantine HCl

Memantine HCl Structure
  • ₹8183.7 - ₹23400
  • Product name: Memantine HCl
  • CAS: 41100-52-1
  • MF: C12H22ClN
  • MW: 215.76
  • EINECS:255-219-6
  • MDL Number:MFCD00214336
  • Synonyms:MEMANTINE HCL;LABOTEST-BB LT00233220;1,3-Dimethyl-5-aminoadamantane hydrochloride;1,3-DIMETHYLAMINOADAMANTANE HYDROCHLORIDE;1-AMINO-3,5-DIMETHYLADAMANTANE HCL;1-AMINO-3,5-DIMETHYLADAMANTANE HYDROCHLORIDE;1-AMINO-3,4-DIMETHYLADAMANTANE HYDROCHLORIDE;3,5-DIMETHYLAMANTADINE HYDROCHLORIDE
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberD3608
  • Product description3,5-Dimethyl-1-adamantanamine Hydrochloride
  • Packaging5G
  • Price₹12700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD3608
  • Product description3,5-Dimethyl-1-adamantanamine Hydrochloride
  • Packaging25G
  • Price₹23400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM9292
  • Product descriptionMemantine hydrochloride ≥98% (GC)
  • Packaging25MG
  • Price₹8183.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM9292
  • Product descriptionMemantine hydrochloride ≥98% (GC)
  • Packaging100MG
  • Price₹21030
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1886
  • Product descriptionMemantine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹22743.33
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D3608 3,5-Dimethyl-1-adamantanamine Hydrochloride 5G ₹12700 2022-05-26 Buy
TCI Chemicals (India) D3608 3,5-Dimethyl-1-adamantanamine Hydrochloride 25G ₹23400 2022-05-26 Buy
Sigma-Aldrich(India) M9292 Memantine hydrochloride ≥98% (GC) 25MG ₹8183.7 2022-06-14 Buy
Sigma-Aldrich(India) M9292 Memantine hydrochloride ≥98% (GC) 100MG ₹21030 2022-06-14 Buy
Sigma-Aldrich(India) PHR1886 Memantine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹22743.33 2022-06-14 Buy

Properties

Melting point :292 °C
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in Water (up to 20 mg/ml)
form :Fine Powder
color :White
Water Solubility :Soluble in water (100mM)
Merck :14,5806
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
InChI :InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
InChIKey :LDDHMLJTFXJGPI-UHFFFAOYSA-N
SMILES :C12(N)CC3(C)CC(CC(C)(C3)C1)C2.[H]Cl
CAS DataBase Reference :41100-52-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer’s disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European. The development of Alzheimer’s disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity. Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs). Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington’s disease, ALS and movement disorders, among other.

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Suppliers and manufacturers

Jigs Chemical ltd Dr. Reddy's Laboratories Ltd Global Pharma KARPSCHEM LABORATORIES Vivimed Labs Ltd Macleods Pharmaceuticals Limited Hetero Drugs Limited Hikal Ltd. Nosch Labs Pvt Ltd Orchid Pharma Ltd. (Formerly Known as Orchid Chemicals and Pharmaceuticals Ltd.)