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Memantine HCl

Memantine HCl

CAS:
41100-52-1
MF:
C12H22ClN
MW:
215.76

Properties

Melting point:
292 °C
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in Water (up to 20 mg/ml)
form 
Fine Powder
color 
White
Water Solubility 
Soluble in water (100mM)
Merck 
14,5806
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
InChI
InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
InChIKey
LDDHMLJTFXJGPI-UHFFFAOYSA-N
SMILES
C12(N)CC3(C)CC(CC(C)(C3)C1)C2.[H]Cl

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H315-H319
Precautionary statements 
P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29213000

Use

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimers disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European. The development of Alzheimers disease involves the misfolded mutant proteins such as -amyloid peptide (A, particularly A142). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity. Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs). Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntingtons disease, ALS and movement disorders, among other.

92 India supplier list of "Memantine HCl"

  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:MemantineHCl
  • Products Intro:Purity: 99% | Package: 25 Kgs
  • Company Type: Trader
  • Country/Region: Maharashtra,INDIA
  • Product Name:Memantine Hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Memantine hydrochloride
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA

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