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6-ANILINO-5,8-QUINOLINEDIONE

6-ANILINO-5,8-QUINOLINEDIONE Structure
  • ₹16529.78
  • Product name: 6-ANILINO-5,8-QUINOLINEDIONE
  • CAS: 91300-60-6
  • MF: C15H10N2O2
  • MW: 250.25
  • EINECS:
  • MDL Number:MFCD00210756
  • Synonyms:6-ANILINOQUINOLINE-5,8-QUINONE;6-(Phenylamino)-5,8-quinolinedione, LY-83,583;6-(anilino)quinoline-5,8-dione;6-(phenylamino)quinoline-5,8-dione;5,8-Dihydro-5,8-dioxo-6-(phenylaMino)quinoline;5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline, [(5,8-Dihydro-5,8-dioxoquinolin-6-yl)amino]benzene, 6-Anilinoquinoline-5,8-dione;LY 83583;6-(PHENYLAMINO)-5,8-QUINOLINEDIONE
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA6563
  • Product description6-Anilinoquinoline-5,8-quinone ≥95% (TLC), solid
  • Packaging5MG
  • Price₹16529.78
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A6563 6-Anilinoquinoline-5,8-quinone ≥95% (TLC), solid 5MG ₹16529.78 2022-06-14 Buy

Properties

Melting point :184-185°C
Boiling point :446.9±45.0 °C(Predicted)
Density :1.400±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :0.1 M HCl: 1 mg/mL
form :solid
pka :-0.63±0.20(Predicted)
color :violet
CAS DataBase Reference :91300-60-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

LY83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC50 value of 2 μM. LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 μM and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki value of 3 μM.

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