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ChemicalBook > Product Catalogue >API >Digestive system drugs >Liver Disease drugs >Protoporphyrin IX

Protoporphyrin IX

Protoporphyrin IX Structure
  • ₹12809.4 - ₹39069
  • Product name: Protoporphyrin IX
  • CAS: 553-12-8
  • MF: C34H34N4O4
  • MW: 562.66
  • EINECS:209-033-7
  • MDL Number:MFCD00151109
  • Synonyms:KAMMERER'S PORPHYRIN;21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-;7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid;Kammerer's prophyrin;PROTOPORPHYRIN-'IX', FOR FLUORESCENCE;ProtoporphyrinIXforfluorescence95+%;PROTOPORPHYRINIX,FREEACID;Kammerers porphyrin, Ooporphyrin, 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 1gm
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberP8293
  • Product descriptionProtoporphyrin IX ≥95%
  • Packaging1G
  • Price₹12809.4
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number P 3314
  • Product descriptionProtoporphyrin IX, ≥95%
  • Packaging1gm
  • Price₹39069
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P8293 Protoporphyrin IX ≥95% 1G ₹12809.4 2022-06-14 Buy
ottokemi P 3314 Protoporphyrin IX, ≥95% 1gm ₹39069 2022-05-26 Buy

Properties

Melting point :>300 °C(Solv: acetone (67-64-1))
Boiling point :629.06°C (rough estimate)
Density :1.1829 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly)
form :Powder
color :purple
Water Solubility :106.9mg/L(25 ºC)
Sensitive :light sensitive
Merck :13,7990
BRN :380795
Stability :Light Sensitive
InChIKey :FEDYMSUPMFCVOD-UJJXFSCMSA-N
CAS DataBase Reference :553-12-8
NIST Chemistry Reference :Protoporphyrin-1x(553-12-8)
EPA Substance Registry System :Protoporphyrin IX (553-12-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Protoporphyrin-9 is the key porphyrin in animal and plant cells, presenting a precursor scaffold for heme sites and other metal domains contained in metalloproteins. Iron is introduced to the porphyrin to generate heme, the primary oxygen-binding moiety found in proteins. Protoporphyrin-9 as heme is incorporated into hemoglobin, catalase, peroxidase, and certain cytochrome enzymes. Introduction of magnesium into Protoporphyrin-9 and subsequent transformations generates chlorophyll, the main light energy-gathering pigment in plants necessary for photosynthesis. Protoporphyrin-9 is also demonstrated to activate guanylate cyclase, indicating that cellular levels of Protoporphyrin-9 and heme may serve to regulate guanylate cyclase activity and tissue cyclic GMP levels. λex 402 nm, 409 nm λem 625 nm, 633 nm

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