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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >Protocatechuic acid

Protocatechuic acid

Protocatechuic acid Structure
  • ₹1269 - ₹34002
  • Product name: Protocatechuic acid
  • CAS: 99-50-3
  • MF: C7H6O4
  • MW: 154.12
  • EINECS:202-760-0
  • MDL Number:MFCD00002509
  • Synonyms:3,4-Dihydroxybenzoic acid >=97.0% (T);Carbohydroquinonic acid;Hypogallic acid;3,4-Dihydroxybenzoic acid, >=99%;Benzoic acid, 3,4-dihydroxy-;PROTOCATECHUIC ACID(RG);3,4-DIHYDROXYBENZOIC ACID / PROTOCATECHUIC ACID;4-Carboxy-1,2-dihydroxybenzene
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 50MG
  • 10gm
  • 25gm
  • 25G
  • 100gm
  • 100G
  • 500gm
  • ManufacturerTCI Chemicals (India)
  • Product numberC0055
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging25G
  • Price₹5300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC0055
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging100G
  • Price₹8600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number37580
  • Product description3,4-Dihydroxybenzoic acid ≥97.0% (T)
  • Packaging25G
  • Price₹5693.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number08992
  • Product description3,4-Dihydroxybenzoic acid analytical standard
  • Packaging50MG
  • Price₹9731.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number37580
  • Product description3,4-Dihydroxybenzoic acid ≥97.0% (T)
  • Packaging100G
  • Price₹14862.73
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number P 2700
  • Product descriptionProtocatechuic acid 98%
  • Packaging10gm
  • Price₹1269
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 2700
  • Product descriptionProtocatechuic acid 98%
  • Packaging25gm
  • Price₹2205
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 2700
  • Product descriptionProtocatechuic acid 98%
  • Packaging100gm
  • Price₹7749
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number P 2700
  • Product descriptionProtocatechuic acid 98%
  • Packaging500gm
  • Price₹34002
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C0055 3,4-Dihydroxybenzoic Acid 25G ₹5300 2022-05-26 Buy
TCI Chemicals (India) C0055 3,4-Dihydroxybenzoic Acid 100G ₹8600 2022-05-26 Buy
Sigma-Aldrich(India) 37580 3,4-Dihydroxybenzoic acid ≥97.0% (T) 25G ₹5693.95 2022-06-14 Buy
Sigma-Aldrich(India) 08992 3,4-Dihydroxybenzoic acid analytical standard 50MG ₹9731.68 2022-06-14 Buy
Sigma-Aldrich(India) 37580 3,4-Dihydroxybenzoic acid ≥97.0% (T) 100G ₹14862.73 2022-06-14 Buy
ottokemi P 2700 Protocatechuic acid 98% 10gm ₹1269 2022-05-26 Buy
ottokemi P 2700 Protocatechuic acid 98% 25gm ₹2205 2022-05-26 Buy
ottokemi P 2700 Protocatechuic acid 98% 100gm ₹7749 2022-05-26 Buy
ottokemi P 2700 Protocatechuic acid 98% 500gm ₹34002 2022-05-26 Buy

Properties

Melting point :197-200 °C (dec.) (lit.)
Boiling point :237.46°C (rough estimate)
Density :1.54
refractive index :1.6400 (estimate)
FEMA :4430 | 3,4-DIHYDROXYBENZOIC ACID
storage temp. :Store below +30°C.
solubility :20g/l
pka :4.48(at 25℃)
form :Fine Crystalline Powder
color :Beige to brown
PH :3.78(1 mM solution);3.25(10 mM solution);2.74(100 mM solution)
Odor :at 100.00 %. mild phenolic balsamic
Odor Type :phenolic
Water Solubility :Soluble in hot alcohol and ether. Slightly soluble in water.
Sensitive :Air Sensitive
Merck :14,7894
BRN :1448841
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey :YQUVCSBJEUQKSH-UHFFFAOYSA-N
LogP :1.16
CAS DataBase Reference :99-50-3(CAS DataBase Reference)
EPA Substance Registry System :Protocatechuic acid (99-50-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Protocatechuic acid (PCA) is a dihydroxybenzoic acid phenolic compound found in many edible and medicinal plants. It is a major metabolite of antioxidant polyphenols found in green tea and demonstrates free radical scavenging capability in a 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity assay (IC50 = 16.3 μM). It is thought to possess anti-inflammatory, antihyperglycemic, neuroprotective, and anticancer activities. Dietary administration of PCA dose dependently inhibits in vitro chemical carcinogenesis and exerts pro-apoptotic and anti-proliferative effects in different tissues. In studies of tumor cell migration and invasion using mouse melanoma B16/F10 cells, PCA at 0.1-2 mM down-regulated the Ras/Akt/NF-κB pathway by targeting RhoB activation, leading to a reduction of MMP-mediated activity.

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