NS-2028
- ₹26600.01 - ₹104850.95
- Product name: NS-2028
- CAS: 204326-43-2
- MF: C9H5BrN2O3
- MW: 269.05
- EINECS:
- MDL Number:MFCD01530052
- Synonyms:NS-2028;8-BROMO-4H-2,5-DIOXA-3,9B-DIAZA CYCLOPENTA[A]NAPHTHALEN-1-ONE;4H-8-BROMO-1,2,4-OXADIAZOLO(3,4-D)BENZ(B)(1,4)OXAZIN-1-ONE;4H-8-BROMO-1,2,4-OXADIAZOLO(3,4-D)BENZO(B)(1,4)OXAZIN-1-ONE;4-H-BROMO-1,2,4-OXADIAZOLE(3,4-ALPHA)BENZ(B)OXAZIN-1-ONE;NS 2028 - CAS 204326-43-2 - Calbiochem;8-Bromo-1H,4H-[1,2,4]Oxadiazolo[3,4-c][1,4]Benzoxazin-1-One;8-bromo-4~{H}-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product number492030
- Product descriptionNS 2028 - CAS 204326-43-2 - Calbiochem Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase.
- Packaging5MG
- Price₹26600.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN211
- Product descriptionNS 2028 solid
- Packaging5MG
- Price₹26802.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN211
- Product descriptionNS 2028 solid
- Packaging25MG
- Price₹104850.95
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 492030 | NS 2028 - CAS 204326-43-2 - Calbiochem Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase. | 5MG | ₹26600.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N211 | NS 2028 solid | 5MG | ₹26802.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N211 | NS 2028 solid | 25MG | ₹104850.95 | 2022-06-14 | Buy |
Properties
Melting point :160~170℃
Boiling point :353.8±52.0 °C(Predicted)
Density :2.06±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMSO: 13 mg/mL
pka :-1.18±0.20(Predicted)
form :solid
color :white
Boiling point :353.8±52.0 °C(Predicted)
Density :2.06±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMSO: 13 mg/mL
pka :-1.18±0.20(Predicted)
form :solid
color :white
Safety Information
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Description
NS-2028 is a specific inhibitor of soluble guanylyl cyclase. It inhibits purified bovine lung guanylyl cyclase in a concentration dependent and irreversible manner with IC50 values of 30 and 200 nM for basal and NO-stimulated enzymes, respectively. S-nitroso-glutathione-enhanced guanylyl cyclase activity in mouse cerebellum homogenates is inhibited by NS-2028 with an IC50 value of 17 nM, making it about 4.7 fold more potent than ODQ, which has an IC50 value of 80 nM for inhibition of soluble guanylyl cyclase in the same assay. NS-2028 does not inhibit particulate guanylyl cyclase or adenylyl cyclase.More related product prices
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