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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Nicardipine hydrochloride

Nicardipine hydrochloride

Nicardipine hydrochloride Structure
  • ₹8900 - ₹79834.38
  • Product name: Nicardipine hydrochloride
  • CAS: 54527-84-3
  • MF: C26H30ClN3O6
  • MW: 515.99
  • EINECS:259-198-4
  • MDL Number:MFCD00057327
  • Synonyms:methyl 2-(benzyl-methyl-amino)ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride;2-(benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylatemonohydrochloride;Naratriptan HCl;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Methyl 2-[Methyl(phenylmethyl)amino]ethyl Ester Hydrochloride;Antagonyl;Barizin;Dacarel;Vasonas
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1G
  • 5G
  • 10G
  • ManufacturerTCI Chemicals (India)
  • Product numberN0635
  • Product descriptionNicardipine Hydrochloride
  • Packaging5G
  • Price₹8900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7510
  • Product descriptionNicardipine hydrochloride powder, ≥98%
  • Packaging1G
  • Price₹12632.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2531
  • Product descriptionNicardipine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹22764.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7510
  • Product descriptionNicardipine hydrochloride powder, ≥98%
  • Packaging5G
  • Price₹49513.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN7510
  • Product descriptionNicardipine hydrochloride powder, ≥98%
  • Packaging10G
  • Price₹79834.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) N0635 Nicardipine Hydrochloride 5G ₹8900 2022-05-26 Buy
Sigma-Aldrich(India) N7510 Nicardipine hydrochloride powder, ≥98% 1G ₹12632.78 2022-06-14 Buy
Sigma-Aldrich(India) PHR2531 Nicardipine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹22764.98 2022-06-14 Buy
Sigma-Aldrich(India) N7510 Nicardipine hydrochloride powder, ≥98% 5G ₹49513.55 2022-06-14 Buy
Sigma-Aldrich(India) N7510 Nicardipine hydrochloride powder, ≥98% 10G ₹79834.38 2022-06-14 Buy

Properties

Melting point :176-1780C
storage temp. :2-8°C
solubility :DMSO: ~1 mg/mL
form :powder
color :yellow
Merck :14,6495
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water or ethanol may be stored at -20°C for up to 1 month.
InChIKey :AIKVCUNQWYTVTO-UHFFFAOYSA-N
CAS DataBase Reference :54527-84-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Nicardipine is a dihydropyridine L-type calcium channel antagonist that displays antihypertensive and antianginal activity. It is reported to inhibit adenosine A1, A2A, and A3 receptors with Ki values of 19.6, 63.8, and 3.25 μM, respectively, and can inhibit cytochrome P450 3A4 catalytic activity with an IC50 value of 0.148 μM. Additionally, nicardipine has been shown to activate transient receptor potential A1 channels, producing an increase in Ca2+ (EC50 = 0.5 μM).

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Suppliers and manufacturers

Gland Pharma Ltd Rivashaa Agrotech Biopharma Pvt. Ltd. Apothecon Pharmaceuticals Pvt., Ltd. Kebee Pharmachemie Pvt., Ltd. GLAND PHARMA LTD CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd. SynZeal Research Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd