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IOX2

IOX2 Structure
CAS No.
931398-72-0
Chemical Name:
IOX2
Synonyms
IOX2;JICL38;CS-564;IOX 2, >=98%;IOX2(Glycine);IOX-2; IOX2; IOX 2;DesidustatImpurity1;IOX2;IOX 2;IOX-2;JICL38;(1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine;2-[(1-BENZYL-4-HYDROXY-2-OXOQUINOLINE-3-CARBONYL)AMINO]ACETIC ACID
CBNumber:
CB32638323
Molecular Formula:
C19H16N2O5
Molecular Weight:
352.34
MOL File:
931398-72-0.mol
Modify Date:
2023/6/30 15:45:59

IOX2 Properties

Boiling point 642.8±55.0 °C(Predicted)
Density 1.470±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble5mg/mL, clear (warmed)
pka 3.61±0.10(Predicted)
form powder
color white to beige
InChIKey CAOSCCRYLYQBES-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
NFPA 704
0
2 0

IOX2 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0652 IOX2 ≥98% (HPLC) 931398-72-0 5MG ₹12611.13 2022-06-14 Buy
Sigma-Aldrich(India) SML0652 IOX2 ≥98% (HPLC) 931398-72-0 25MG ₹48777.45 2022-06-14 Buy
Product number Packaging Price Buy
SML0652 5MG ₹12611.13 Buy
SML0652 25MG ₹48777.45 Buy

IOX2 Chemical Properties,Uses,Production

Uses

IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM.

Biochem/physiol Actions

IOX2 is selective and potent inhibitor of prolyl hydroxylases (PHD). Stabilization of HIF-1R through inhibition of PHD has been examined as a potential treatment for ischemic diseases including anemia, myocardial infarction, and stroke. IOX2 is a selective inhibitor of the hypoxia inducible factor (HIF) prolyl-hydroxylases (PHD) that exhibits up-regulation of HIF1a in zebrafish. For full characterization details, please visit the IOX2 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

IOX2 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 126)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32951 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29884 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39894 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd +86-86-22-87899925 +86-8618522618860 China 694 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32080 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry

IOX2 Spectrum

931398-72-0(IOX2)Related Search:

Glycine, N-[[1,2-dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]- N-[[4-Hydroxy-2-oxo-1-(phenylmethyl)-1,2-dihydro-3-quinolinyl]carbonyl]glycine IOX2 JICL38 N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]-glycine (1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine IOX 2, >=98% IOX2;IOX 2;IOX-2;JICL38 IOX2 2-(1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxaMido)acetic acid 2-[(1-BENZYL-4-HYDROXY-2-OXOQUINOLINE-3-CARBONYL)AMINO]ACETIC ACID N-[[4-Hydroxy-2-oxo-1-(phenylmethyl)-1,2-dihydro-3-quinolinyl]carbonyl]glycine IOX2(Glycine) IOX-2; IOX2; IOX 2 CS-564 DesidustatImpurity1 HIF-PH,Inhibitor,inhibit,HIF/HIF Prolyl-Hydroxylase,IOX-2,IOX2,HIFs,Hypoxia-inducible factors 931398-72-0 Inhibitors Inhibitor