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GO 6976

CAS No.: 136194-77-9

Chemical Name:: GO 6976

Synonyms: G6976;GO 6976;GOE 6976;PD406976;Aids044729;Aids-044729;Go6976 Go-6976;Go6976 (PD40697);GO 6976 USP/EP/BP;InSolution? G? 6976

CBNumber:: CB1396876

Molecular Formula:: C24H18N4O

Molecular Weight:: 378.43

MOL File:: 136194-77-9.mol

Modify Date:: 2023/6/30 15:45:59

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GO 6976 Properties

Melting point	>221°C (dec.)
Boiling point	652.3±55.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Acetonitrile (Very Slightly, Heated), DMSO (Slightly), Methanol (Very Slightly)
form	Off-white solid
pka	14.39±0.20(Predicted)
color	White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Safety Statements	22-24/25
HS Code	2933998090

GO 6976 price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	365250	Gö 6976 - CAS 136194-77-9 - Calbiochem G? 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC?? = 7.9 nM for rat brain). Exhibits selectively fo	136194-77-9	1MG	₹22650	2022-06-14	Buy
Sigma-Aldrich(India)	365253	InSolution Gö 6976 - CAS 136194-77-9 - Calbiochem	136194-77-9	1ML	₹25060	2022-06-14	Buy
Sigma-Aldrich(India)	365250	Gö 6976 - CAS 136194-77-9 - Calbiochem G? 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC?? = 7.9 nM for rat brain). Exhibits selectively fo	136194-77-9	500μG	₹26950	2022-06-14	Buy

Product number	Packaging	Price	Buy
365250	1MG	₹22650	Buy
365253	1ML	₹25060	Buy
365250	500μG	₹26950	Buy

GO 6976 Chemical Properties,Uses,Production

Uses

Go 6976 is a potent FLT3 inihibtor which is been shown to initiate cytotoxicity involving acute leukemia. Also known as a PKC inhibitor, which results into apoptosis and tumor destruction. Cancer therapeutic agent.

Biological Activity

Potent protein kinase C (PKC) inhibitor (IC 50 = 7.9 nM). In vitro, discriminates between Ca 2+ -dependent and -independent isoforms of PKC; selectively inhibits PKC α and PKC β 1 (IC 50 values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKC δ , - ε , or - ζ (IC 50 > 3 μ M). Also inhibits TrkA, TrkB, JAK2 and JAK3 tyrosine kinases (IC 50 values are 5, 30, 130 and 370 nM respectively).

GO 6976 Preparation Products And Raw materials

Raw materials

Preparation Products

GO 6976 Suppliers

Global( 122)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3136	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	26216	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
career henan chemical co	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

GO 6976 Spectrum

GO 6976(136194-77-9)¹HNMR

136194-77-9(GO 6976)Related Search:

Indole-5-carboxaldehyde N-Ethyl-3-carbazolecarboxaldehyde 4-AMINOMETHYLINDOLE 1-(1-METHYL-1H-INDOL-4-YL)METHYLAMINE 97 N-(2-CYANOETHYL)PYRROLE

Indole-4-carboxaldehyde 3-Formyl-9H-carbazole GO 6976 1-Methylindoline-5-carboxaldehyde 97% C-(9-ETHYL-9H-CARBAZOL-3-YL)-METHYLAMINE

3-METHYLCARBAZOLE 1H-INDOLE-5-CARBOXAMIDE, 97% 1-ethyl-1H-indole-5-carbaldehyde 11,12-Dihydroindolo[2,3-a]carbazole (1-METHYL-1H-INDOL-5-YL)METHYLAMINE

1-METHYL-1H-INDOLE-4-CARBALDEHYDE C-(1H-INDOL-5-YL)-METHYLAMINE K-252C

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InSolution? G? 6976 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile Go6976,5,6,7,13-Tetrahydro-13-Methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile PD406976 12-(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO(2,3-A)PYRROLO(3,4-C)-CARBAZOLE 12-2(2-CYANOETHYL)-6,7,12,13-TETRAHYDRO-13-METHYL-5-OXO-5H-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE GO 6976 G6976 GOE 6976 Go 6976, 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole 12H-Indolo[2,3-A]pyrrolo[3,4-C]carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo- Aids044729 Aids-044729 InSolution G 6976 - CAS 136194-77-9 - Calbiochem GO 6976 USP/EP/BP 3-(13-Methyl-5-oxo-6,7-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-12(13H)-yl)propanenitrile Go6976 (PD40697) Go6976 Go-6976 Go 6976 (DMSO solution) 136194-77-9 Inhibitors Inhibitor