VU 0365114

CAS No.: 1208222-39-2

Chemical Name:: VU 0365114

Synonyms: VU 0365114;1-Biphenyl-4-ylmethyl-5-trifluoromethoxy-1H-indole-2,3-dione;1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione;1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione;1H-Indole-2,3-dione, 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)-;VU 0365114,inhibit,Muscarinic acetylcholine receptor,VU0365114,Inhibitor,VU-0365114,mAChR

CBNumber:: CB32652655

Molecular Formula:: C22H14F3NO3

Molecular Weight:: 397.35

MOL File:: 1208222-39-2.mol

Modify Date:: 2024/11/4 20:04:50

Request For Quotation

VU 0365114 Properties

Boiling point	526.2±60.0 °C(Predicted)
Density	1.386±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Ethanol:10.0(Max Conc. mg/mL);25.17(Max Conc. mM) DMSO:30.0(Max Conc. mg/mL);75.5(Max Conc. mM) DMF:30.0(Max Conc. mg/mL);75.5(Max Conc. mM)
form	Powder
pka	-3.71±0.20(Predicted)
color	Light yellow to orange

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

VU 0365114 Chemical Properties,Uses,Production

Uses

VU 0365114 is a selective positive allosteric modulator of M5 (EC50 values are 2.7 μM for human M5, and >30 μM for M1, M2, M3 and M4 receptors).

VU 0365114 Preparation Products And Raw materials

Raw materials

Preparation Products

VU 0365114 Suppliers

Global( 56)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6100	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32063	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49734	58	Inquiry
TargetMol Chemicals Inc.		United States	38463	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57505	58	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48461	58	Inquiry
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	China	3547	58	Inquiry
Henan Alpha Chemical Co., Ltd.	0371-55013243 15324716602	China	9999	58	Inquiry
Bide Pharmatech Ltd.	400-1647117 13681763483	China	62163	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
Jinan Jiuli Biotechnology Co. , Ltd.	58
Henan Alpha Chemical Co., Ltd.	58
Bide Pharmatech Ltd.	58

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VU 0365114 1-Biphenyl-4-ylmethyl-5-trifluoromethoxy-1H-indole-2,3-dione 1-[(1,1'-Biphenyl)-4-ylmethyl]-5-(trifluoromethoxy)-1H-indole-2,3-dione 1H-Indole-2,3-dione, 1-([1,1'-biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)- VU 0365114,inhibit,Muscarinic acetylcholine receptor,VU0365114,Inhibitor,VU-0365114,mAChR 1-([1,1'-Biphenyl]-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione 1208222-39-2 Pharmaceuticals Amines Aromatics Heterocycles Intermediates & Fine Chemicals