VU0483605

CAS No.: 1623101-11-0

Chemical Name:: VU0483605

Synonyms: VU0483605;3-Chloro-N-(3-chloro-4-(4-chloro-1,3-dioxoisoindolin-2-yl)phenyl)picolinamide;3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide;2-Chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)phenyl]nicotinamide;3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide;3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]pyridine-2-carboxamide;2-Pyridinecarboxamide, 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-;Inhibitor,inhibit,VU0483605,Metabotropic glutamate receptors,allosteric modulator,brain penetrant,metabotropic glutamate,VU 0483605,mGluR,VU-0483605

CBNumber:: CB63067594

Molecular Formula:: C20H10Cl3N3O3

Molecular Weight:: 446.67

MOL File:: 1623101-11-0.mol

Modify Date:: 2024/7/2 8:55:13

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VU0483605 Properties

Density	1.625±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	≤20mg/ml in DMSO;20mg/ml in dimethyl formamide
form	crystalline solid
pka	9.39±0.70(Predicted)
color	Light yellow to orange

VU0483605 Chemical Properties,Uses,Production

Uses

VU 0483605 is a positive allosteric modulator of metabotropic glutamate receptors (mGluRs) that preferentially binds mGlu1 over mGlu4 (1,2). VU 0483605 is a mGlu1 antagonist and has potential therapeutic properties for treating schizophrenia.

VU0483605 Preparation Products And Raw materials

Raw materials

Preparation Products

VU0483605 Suppliers

Global( 36)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49739	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Tocris Bioscience	+44 (0) 117 916 3333	United Kingdom	5729	77	Inquiry
United States Biological	1-800-520-3011	United States	6106	58	Inquiry
ApexBio Technology	+ 1-832-696-8203	United States	6254	58	Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd.	15800340161	CHINA	6846	58	Inquiry
Beijing Fubo Biotechnology Co., Ltd.	010-57263844 13260236521	CHINA	6039	58	Inquiry
Shanghai Minmin Biotechnology Co., Ltd.	18021003406	CHINA	6530	58	Inquiry
Shanghai Yaoyun Biological Technology Co., Ltd.	400-002-6926 400-002-6926	CHINA	6852	58	Inquiry

Supplier	Advantage
BOC Sciences	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Amadis Chemical Company Limited	58
Tocris Bioscience	77
United States Biological	58
ApexBio Technology	58
Shanghai Hao Zhun Biological Technology Co., Ltd.	58
Beijing Fubo Biotechnology Co., Ltd.	58
Shanghai Minmin Biotechnology Co., Ltd.	58
Shanghai Yaoyun Biological Technology Co., Ltd.	58

VU0483605 Spectrum

VU0483605(1623101-11-0)¹HNMR

1623101-11-0(VU0483605)Related Search:

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VU 0364439 VU0650786 VU0661013

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VU0483605 2-Chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)phenyl]nicotinamide 3-Chloro-N-(3-chloro-4-(4-chloro-1,3-dioxoisoindolin-2-yl)phenyl)picolinamide 3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide 2-Pyridinecarboxamide, 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]- 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]pyridine-2-carboxamide 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide Inhibitor,inhibit,VU0483605,Metabotropic glutamate receptors,allosteric modulator,brain penetrant,metabotropic glutamate,VU 0483605,mGluR,VU-0483605 1623101-11-0 C20H10Cl3N3O3