5-Fluoro-2-methylindole
- CAS No.
- 399-72-4
- Chemical Name:
- 5-Fluoro-2-methylindole
- Synonyms
- 5-FLUORO-2-METHYL-1H-INDOLE;5-FLUORO-2-METHYLINDOLE;1H-Indole, 5-fluoro-2-methyl-;5-Fluoro-2-methyl-1H-indole 97%
- CBNumber:
- CB3294509
- Molecular Formula:
- C9H8FN
- Molecular Weight:
- 149.16
- MOL File:
- 399-72-4.mol
- Modify Date:
- 2024/3/27 14:23:02
| Melting point | 98-101 °C (lit.) |
|---|---|
| Boiling point | 112-120C |
| Density | 1.219±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 16.73±0.30(Predicted) |
| form | Solid |
| color | Light yellow to Brown |
| InChI | InChI=1S/C9H8FN/c1-6-4-7-5-8(10)2-3-9(7)11-6/h2-5,11H,1H3 |
| InChIKey | JJIUISYYTFDATN-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(F)C=C2)C=C1C |
| CAS DataBase Reference | 399-72-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P304+P340-P405-P501a | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 36/37/38-25 | |||||||||
| Safety Statements | 26-36-45-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
5-Fluoro-2-methylindole price More Price(2)
5-Fluoro-2-methylindole Chemical Properties,Uses,Production
Description
5-Fluoro-2-methylindole is a chemical intermediate that can be used in the synthesis of other compounds. It is a versatile building block with many applications, such as being a useful intermediate for the synthesis of heterocyclic compounds. This compound reacts with aniline to form 2,6-diaminopyridine, which has been shown to have anti-inflammatory properties.
General Description
5-Fluoro-2-methylindole (5-Fluoro-2-methyl-1H-indole) is a 5-substituted-2-methyl-1H-indole.
Synthesis
1-(5-fluoro-2-nitrophenyl) propane-2-one (0.5mmol, 99 mg), zinc powder (3.0mmol, 196 mg), and acetic acid (6.0mmol, 360 mg) was added to the reaction tube, followed by adding ethanol to 2 ml at 90 °C for 3h. After cooling to room temperature, the reaction system was added 20 ml water. 5-Fluoro-2-methylindole was obtained after purification. 
Solubility in water
Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water.
5-Fluoro-2-methylindole Preparation Products And Raw materials
Raw materials
1of3
chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TANUJ PYRIDINE | 8790371027 | Hyderabad, India | 107 | 58 | Inquiry |
| CHATURYA BIOTECH | +91-7702707258 +91-7702707258 | Telangana, India | 479 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Oceanic Pharmachem Pvt. Ltd. | 91-22-42128600 | Maharashtra, India | 2006 | 58 | Inquiry |
| Vijay Chemicals | 08048971555 | Pune, India | 50 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| Dhanvi Exim Services | 91--8790148237 | Hyderabad, India | 204 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| TANUJ PYRIDINE | 58 |
| CHATURYA BIOTECH | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| CHEMSWORTH | 30 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Oceanic Pharmachem Pvt. Ltd. | 58 |
| Vijay Chemicals | 58 |
| Vyas Bio Life Sciences Pvt. Ltd | 58 |
| Dhanvi Exim Services | 58 |