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TAMARIXETIN

TAMARIXETIN Structure
CAS No.
603-61-2
Chemical Name:
TAMARIXETIN
Synonyms
Aids098167;amarixetin;Chiosmethin;TAMARIXETIN;Aids-098167;tamaraxetin;TAMARIEXETIN;4’-methylquercetin;4’-methoxyquercetin;4’-o-methylquercetin
CBNumber:
CB3328499
Molecular Formula:
C16H12O7
Molecular Weight:
316.26
MOL File:
603-61-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:06

TAMARIXETIN Properties

Melting point 265-268°C
Boiling point 601.8±55.0 °C(Predicted)
Density 1.634±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: Slightly Soluble; Methanol: Slightly Soluble
form A solid
pka 6.31±0.40(Predicted)
color Yellow to brown
LogP 2.420 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
Risk Statements  22
Safety Statements  22-45
NFPA 704
0
2 0

TAMARIXETIN Chemical Properties,Uses,Production

Description

4''-O-methyl Quercetin is a flavonoid isolated from C. ordata with anticancer and antiplasmodial activity. 4''-O-methyl Quercetin is a major metabolite of quercetin (Item No. 10005169) that inhibits the viability of HL-60, U937, MOLT-3, Raji, K562, MCF-7, SK-MEL-1, and A549 human tumor cell lines with IC50 values ranging from 5.5-24.1 μM. It induces G2-M arrest and inhibits tubulin polymerization in vitro in a dose-dependent manner. 4''-O-methyl Quercetin inhibits breast cancer resistance protein (BCRP/ABCG2; IC50 = 40 nM in a vesicular transport assay) with no cellular toxicity indicating potential for use in overcoming multidrug resistance in chemotherapy. 4''-O-methyl Quercetin also reduces in vitro proliferation of chloroquine-resistant P. falciparum (IC50 = 4.8 μM) and suppresses infection in mice (65-81% suppression at 2.5-5 mg/kg dose).

Uses

A major metabolite of the flavanoid Quercetin (Q509500) with antioxidant properties. It helps to protect H9c2 cardiomyoblasts against H2O2-induced oxidative stress via the modulation of PI3K/Akt and ERK1/2 signaling pathways.

Definition

ChEBI: A monomethoxyflavone that is quercetin methylated at position O-4'. Isolated from Cyperus teneriffae.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

TAMARIXETIN Preparation Products And Raw materials

Global( 117)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Chengdu Biopurify Phytochemicals Ltd. +86-28-82633860 +86-18080483897 China 3424 58 Inquiry
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ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
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Henan Alfa Chemical Co., Ltd +8618339805032 China 13141 58 Inquiry
3,3',5,7 TETRAHYDROXY-4'-METHOXYFLAVONE TAMARIXETIN QUERCETIN-4'-METHYL ETHER 3,3’,5,7-tetrahydroxy-4’-methoxy-flavon QUERCETIN-4''-METHYL ETHER hplc 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one Chiosmethin 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)- Aids098167 Aids-098167 4'-METHOXY-3,3',5,7-TETRAHYDROXYFLAVONE 4'-METHOXY-3,5,7,3'-TETRAHYDROFLAVONE 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4h-1-benzopyran-4-on 4’-methoxy-3,3’,5,7-tetrahydroxy-flavon 4’-methoxyquercetin 4’-methylquercetin 4’-o-methylquercetin tamaraxetin 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxy-phenyl)chroman-4-one TAMARIEXETIN TAMARIXETIN WITH HPLC 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one amarixetin TamarixetinQ: What is Tamarixetin Q: What is the CAS Number of Tamarixetin Q: What is the storage condition of Tamarixetin Q: What are the applications of Tamarixetin Tamarixetin(3,3',5,7-Tetrahydroxy-4'-Methoxyflavone) 603-61-2 C16H12O7 Aromatics Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Flavanols