DIGITONIN
- CAS No.
- 11024-24-1
- Chemical Name:
- DIGITONIN
- Synonyms
- itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONIN TECH
- CBNumber:
- CB3331307
- Molecular Formula:
- C56H92O29
- Molecular Weight:
- 1229.31
- MOL File:
- 11024-24-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/9 22:15:29
Melting point | 230-240 °C (dec.)(lit.) |
---|---|
Boiling point | 788.4°C (rough estimate) |
alpha | D20 -54° (0.45 g in 15.8 ml methanol) |
Density | 1.1421 (rough estimate) |
refractive index | -52 ° (C=1, EtOH) |
storage temp. | Sealed in dry,Room Temperature |
solubility | H2O: 10 mg/mL at 95 °C hot, clear, colorless |
form | White powder |
pka | 12.68±0.70(Predicted) |
color | white |
optical activity | [α]20/D 54°, c = 2.8 in methanol(lit.) |
Merck | 14,3161 |
BRN | 78654 |
Stability | Hygroscopic |
InChIKey | FAAZZWIYYDUONB-JYIJKGCVSA-N |
EPA Substance Registry System | Digitonin (11024-24-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H301-H373 | |||||||||
Precautionary statements | P301+P310+P330-P314 | |||||||||
Hazard Codes | T | |||||||||
Risk Statements | 23/24/25 | |||||||||
Safety Statements | 22-28-36/37-45 | |||||||||
RIDADR | UN 3462 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | IH2050050 | |||||||||
F | 3-10 | |||||||||
HazardClass | 6.1(a) | |||||||||
PackingGroup | II | |||||||||
HS Code | 29389090 | |||||||||
NFPA 704 |
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DIGITONIN price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D5628 | Digitonin ~50% (TLC) | 11024-24-1 | 1G | ₹46536.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D5628 | Digitonin ~50% (TLC) | 11024-24-1 | 5G | ₹110166.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D141 | Digitonin Used as non-ionic detergent | 11024-24-1 | 100MG | ₹9417.75 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D141 | Digitonin Used as non-ionic detergent | 11024-24-1 | 500MG | ₹30418.25 | 2022-06-14 | Buy |
TCI Chemicals (India) | D0540 | Digitonin | 11024-24-1 | 100MG | ₹5100 | 2022-05-26 | Buy |
DIGITONIN Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.
General Description
Crystals or white powder.
Air & Water Reactions
Forms soapy aqueous suspension .
Reactivity Profile
DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992
Fire Hazard
Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]
DIGITONIN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
Innovative | 07942565925 | Mumbai, India | 617 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Supplier | Advantage |
---|---|
ALPHA CHEMIKA | 43 |
Scientific OEM | 38 |
Sisco Research Laboratories Pvt. Ltd. | 58 |
Otto Chemie Pvt. Ltd. | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Central Drug House(P) Ltd. | 58 |
Triveni chemicals | 58 |
LOBA CHEMIE PVT.LTD. | 58 |
Innovative | 58 |
CLEARSYNTH LABS LTD. | 58 |