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DIGITONIN

DIGITONIN Structure
CAS No.
11024-24-1
Chemical Name:
DIGITONIN
Synonyms
itonin;DIGITIN;igitonin;DIGITONIN;DigitoninGr;5% Digitonin;Digitonin, AR;DIGITONIN(RG);Digitonin USP;DIGITONIN TECH
CBNumber:
CB3331307
Molecular Formula:
C56H92O29
Molecular Weight:
1229.31
MOL File:
11024-24-1.mol
MSDS File:
SDS
Modify Date:
2024/4/9 22:15:29

DIGITONIN Properties

Melting point 230-240 °C (dec.)(lit.)
Boiling point 788.4°C (rough estimate)
alpha D20 -54° (0.45 g in 15.8 ml methanol)
Density 1.1421 (rough estimate)
refractive index -52 ° (C=1, EtOH)
storage temp. Sealed in dry,Room Temperature
solubility H2O: 10 mg/mL at 95 °C hot, clear, colorless
form White powder
pka 12.68±0.70(Predicted)
color white
optical activity [α]20/D 54°, c = 2.8 in methanol(lit.)
Merck 14,3161
BRN 78654
Stability Hygroscopic
InChIKey FAAZZWIYYDUONB-JYIJKGCVSA-N
EPA Substance Registry System Digitonin (11024-24-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H373
Precautionary statements  P301+P310+P330-P314
Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  22-28-36/37-45
RIDADR  UN 3462 6.1/PG 3
WGK Germany  3
RTECS  IH2050050
3-10
HazardClass  6.1(a)
PackingGroup  II
HS Code  29389090
NFPA 704
0
4 0

DIGITONIN price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) D5628 Digitonin ~50% (TLC) 11024-24-1 1G ₹46536.68 2022-06-14 Buy
Sigma-Aldrich(India) D5628 Digitonin ~50% (TLC) 11024-24-1 5G ₹110166.03 2022-06-14 Buy
Sigma-Aldrich(India) D141 Digitonin Used as non-ionic detergent 11024-24-1 100MG ₹9417.75 2022-06-14 Buy
Sigma-Aldrich(India) D141 Digitonin Used as non-ionic detergent 11024-24-1 500MG ₹30418.25 2022-06-14 Buy
TCI Chemicals (India) D0540 Digitonin 11024-24-1 100MG ₹5100 2022-05-26 Buy
Product number Packaging Price Buy
D5628 1G ₹46536.68 Buy
D5628 5G ₹110166.03 Buy
D141 100MG ₹9417.75 Buy
D141 500MG ₹30418.25 Buy
D0540 100MG ₹5100 Buy

DIGITONIN Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.

General Description

Crystals or white powder.

Air & Water Reactions

Forms soapy aqueous suspension .

Reactivity Profile

DIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992

Fire Hazard

Flash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

This digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]

DIGITONIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 297)Suppliers
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ALPHA CHEMIKA +91-22-22061123 +91-22-66382501 Mumbai, India 1681 43 Inquiry
Scientific OEM +91-22- 2343 7546 / 2341 3094 New Delhi, India 1996 38 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Central Drug House(P) Ltd. 91-11-49404040 New Delhi, India 6160 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
LOBA CHEMIE PVT.LTD. 91-22-6663 6699 Mumbai, India 3077 58 Inquiry
Innovative 07942565925 Mumbai, India 617 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
25R,5ALPHA-SPIROSTAN-2ALPHA,3BETA,15BETA-TRIOL 3BETA-O-BETA-D-GALACTOPYRANOSYL-(1->3)-O-BETA-D-GALACTYOPYRANOSYL-(1->2)-O-BETA-D-[3-O-BETA-D-XYLOPYRANOSYL]-(1->4)-O-BETA-D-GALACTOPYRANOSIDE DIGITONIN CRYSTALLINE Digitonin, High Purity DIGITONIN (DIGITIN) HIGH PURITY RECEPTOR SOLUBILIZING DigitoninGr Digitonin, AR DIGITONIN, USED AS NON-IONIC DETERGE beta.-D-Galactopyranoside, (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1?3)-O-.beta.-D-galactopyranosyl-(1?2)-O-.beta.-D-xylopyranosyl-(1?3)-O-.beta.-D-glucopyranosyl-(1?4)- (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-yl O-.beta.-D-glucopyranosyl-(1 .beta.-D-Galactopyranoside DIGITONIN TECH DIGITONIN,CRYSTAL,REAGENT DIGITONIN(RG) (1→3)]-O-β-D-glucopyranosyl-(1→4)- β-D- (2.alpha.,3.beta.,5.alpha.,15.beta.,25R)-2,15-dihydroxyspirostan-3-ylO-.beta.-D-glucopyranosyl-(1.beta.-D-Galactopyranoside beta-d-galactopyranoside,(2alpha,3beta,5alpha,15beta,25theta)-2,15-dihyd osyl-(1.fwdarw.2)-o-[beta-d-xylopyranosyl-(1.fwdarw.3)]-o-beta-d-glucopyranos roxyspirostan-3-ylo-beta-d-glucopyranosyl-(1.fwdarw.3)-o-beta-d-galactopyran yl-(1.fwdarw.4)- Digitonin ,50% 2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl-O-β-D-glucopyranosyl-1β-D-Galactopyranoside DIGITIN DIGITONIN DIGITONIN, ALCOHOL-SOLUBLE DIGITONIN WATER SOLUBLE Digitogenin,3-[O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl- galactopyranoside] Digitonin, approx. 50% (TLC) [(25R)-2α,15β-Dihydroxy-5α-spirostan-3β-yl]4-O-[2-O-[3-O-(β-D-glucopyranosyl)-β-D-galactopyranosyl]-3-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]-β-D-galactopyranoside Digitonin, approx. 50% (TLC) 500MG Digitonin, approx. 50% (TLC) 5GR DIGITONINANALYTICAL GRADE DIGITONIN WATER SOLUBLERESEARCH GRADE Digitonin,Digitin Digitonin, approx. 50%, water soluble 5% Digitonin Digitonin USP itonin β-D-Galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)- Digitonin (Digitin) extrapure, 50% 3-Benzoxazole-6-carboxylic acid igitonin Digitonin (8CI) 11024-24-1 C56H92O29 C56H92O28 Sterols Lipids Non-Ionic Detergents Conjugates Biochemicals and Reagents BioChemical Surfactants (for Biochemistry) Sugars Nonionic Surfactants (for Biochemistry) Glycosides Steroids Steroidglycosides