ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatic acids >2-(4-Bromomethyl)phenylpropionic acid
2-(4-Bromomethyl)phenylpropionic acid
- CAS No.
- 111128-12-2
- Chemical Name:
- 2-(4-Bromomethyl)phenylpropionic acid
- Synonyms
- BMPPA;2-[4-(BROMOMETHYL)PHENYL]PROPIONIC ACID;2-[4-(BROMOMETHYL)PHENYL]PROPANOIC ACID;Loxoprofen 16;Loxoprofen Impurity 28;Loxoprofen Intermediate;p-Bromomethyl isocyanate;Loxoprofen Sodium intermediate;4-(BROMOMETHYL)HYDRATROPIC ACID;2-[4-(Xiu Jiaji)phenyl]propionate
- CBNumber:
- CB3420139
- Molecular Formula:
- C10H11BrO2
- Molecular Weight:
- 243.1
- MOL File:
- 111128-12-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/24 17:31:20
| Melting point | 126-130 °C(lit.) |
|---|---|
| Boiling point | 148°C (rough estimate) |
| Density | 1.4557 (rough estimate) |
| refractive index | 1.5220 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.29±0.10(Predicted) |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C10H11BrO2/c1-7(10(12)13)9-4-2-8(6-11)3-5-9/h2-5,7H,6H2,1H3,(H,12,13) |
| InChIKey | QQXBRVQJMKBAOZ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C(C1=CC=C(CBr)C=C1)C |
| CAS DataBase Reference | 111128-12-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 34-36/37/38 | |||||||||
| Safety Statements | 26-27-36/37/39-45-37/39 | |||||||||
| RIDADR | UN 1759 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | Ⅱ | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
2-(4-Bromomethyl)phenylpropionic acid price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 530360 | 2-[4-(Bromomethyl)phenyl]propionic acid 96% | 111128-12-2 | 25G | ₹38114.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 530360 | 2-[4-(Bromomethyl)phenyl]propionic acid 96% | 111128-12-2 | 25G | ₹38114.83 | 2022-06-14 | Buy |
| TCI Chemicals (India) | B2101 | 2-[4-(Bromomethyl)phenyl]propionic Acid | 111128-12-2 | 5G | ₹6300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B2101 | 2-[4-(Bromomethyl)phenyl]propionic Acid | 111128-12-2 | 25G | ₹19500 | 2022-05-26 | Buy |
2-(4-Bromomethyl)phenylpropionic acid Chemical Properties,Uses,Production
Chemical Properties
beige-cream crystalline powder
General Description
2-[4-(Bromomethyl)phenyl]propionic acid is a propionic acid derivative. Its enthalpy of vaporization at boiling point (421.15K) is 36.363kjoule/mol and density at 25°C is 1.4212g/ml.
Synthesis
The synthesis method comprises the following steps: dissolving sodium hydroxide in excessive methanol to react with p-chloro-tolualdehyde to obtain p-methoxy-tolualdehyde, andthen performing chloromethylation reaction on the p-methoxy tolualdehyde and concentrated hydrochloric acid in the existence of sulfuric acid to obtain p-chloromethyl benzyl ether; performing nucleophilic reaction on the p-chloromethyl benzyl ether and the sodium cyanide to obtain p-methoxy-methyl benzyl cyanide; reacting the p-methoxy-methyl benzyl cyanide with dimethyl carbonate under high pressure in the existence of a catalyst to obtain p-methoxy-methyl benzyl iso-propionitrile; and reacting the p-methoxy-methylbenzyl sodium isopropionate with excessive concentrate sulfuric acid to generate molten salt which is reacted with hydrobromic acid to obtain 2-(4-Bromomethyl)phenylpropionic acid.
2-(4-Bromomethyl)phenylpropionic acid Preparation Products And Raw materials
Global( 523)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GMFC LABS PVT LTD | +91-9133370278 +91-9133370278 | Hyderabad, India | 44 | 58 | Inquiry |
| Allchem Lifescience Pvt. Ltd | +919867655500 | Gujarat, India | 971 | 58 | Inquiry |
| Anlon Healthcare Pvt Ltd | +91-2812562538 +91-7069690081 | Gujarat, India | 54 | 58 | Inquiry |
| Venkata Narayana Active Ingredients Pvt Ltd | +91-9940284484 +91-9840119000 | Tamil Nadu, India | 22 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Santo Righello Pvt. Ltd | 91-9885571757 | Hyderabad, India | 919 | 58 | Inquiry |
| Pharma Direct International | 91-172-2565904 | Haryana, India | 44 | 58 | Inquiry |
| Anlon Healthcare Pvt., Ltd. | 91-281-2562538 | Gujarat, India | 18 | 58 | Inquiry |
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4-(BROMOMETHYL)HYDRATROPIC ACID
2-[(P-BROMOMETHYL)PHENYL]PROPIONIC ACID
2-[4-(Bromomethyl)phenyl]propinic acid
Loxoprofen Intermediate
2-(4-bromomethylphenyl)propionic acid (intermediate of loxoprofen)
2-[4-(bromomethyl)phenyl]propanoic acid (intermediate of loxoprofen)
2-(4-BROMOMETHYL)PHENYLPROPIONIC ACID 97%
2-(4-Bromomethyl)phenylpropionic acid,97%
2-[p-(Bromomethyl)phenyl]propanoic acid
2-((4-Bromomethyl)phenyl)propanic acid
2-(4-BroMoMethyl)phenylpropionic acid, 97% 5GR
2-(4-BoroMoMethyl phenyl)propionic Acid
2-[4-(Bromomethyl)phenyl]propionic acid, 4-(1-Carboxyethyl)benzyl bromide
3-(2-(broMoMethyl)phenyl)propanoic acid
2-[4-(Xiu Jiaji)phenyl]propionate
Loxoprofen Impurity 28
(2R)-2-[4-(bromomethyl)phenyl]propanoate
2-[4-(Bromomethyl)phenyl]propionic Acid >
Benzeneacetic acid, 4-(bromomethyl)-α-methyl-
2- （ 4-Bromomethyl ）c phenylpropionic acid
p-Bromomethyl isocyanate
2-[4-(BROMOMETHYL)PHENYL]PROPANOIC ACID
2-[4-(BROMOMETHYL)PHENYL]PROPIONIC ACID
BMPPA
2-(4-Bromomethyl)phenylpropionic acid Synonyms
Benzeneacetic acid, 4-(bromomethyl)-α-methyl-
Loxoprofen Sodium intermediate
Loxoprofen 16
111128-12-2
11128-12-2
C10H11BrO2
BrCH2C6H4CHCH3CO2H
C10H10BrO2
Building Blocks
C10
Carbonyl Compounds
Carboxylic Acids
Organic Building Blocks
Pharmaceutical intermediate
Organic acids
(intermediate of loxoprofen)
C10
Carbonyl Compounds
Carboxylic Acids
Aromatic Propionic Acids